Extreme diversity of phage amplification rates and phage–antibiotic interactions revealed by PHORCE

PHORCE is a new high-throughput method that enables precise measurement of lytic phage amplification rates in bacterial populations. Using PHORCE, this study reveals broad phenotypic diversity among E. coli and P. aeruginosa phages and shows that phage-antibiotic interactions are primarily determined by the antibiotic.

A breakthrough moment: Researchers discover new class of antibiotics

The last time a new class of antibiotics reached the market was nearly three decades ago—but that could soon change, thanks to a discovery by researchers at McMaster University.

New antibiotic for multidrug resistant superbug

Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhoea. These substances trigger a self-destruction program, which also operates in multi-resistant variants of the pathogen. The novel findings are published in the current issue of Nature Microbiology.

Bifidobacteria support optimal infant vaccine responses - Nature

Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probiotic therapy could be beneficial.

Bluesky

New antibiotic that kills drug-resistant bacteria discovered in technician’s garden

The molecule targets bacteria in a way that other drugs don’t.