Un caso clínico sugiere mejoras temporales en una paciente con alzhéimer tras psilocibina

📰 Título original: Huge Psilocybin Dose Has Incredible Effect on Elderly Dementia Patient

🤖 IA: Es clickbait ⚠️
👥 Usuarios: Es clickbait ⚠️

Ver resumen IA completo https://es.killbait.com/un-caso-clinico-sugiere-mejoras-temporales-en-una-paciente-con-alzheimer-tras-psilocibina.html?utm_source=mastodon_social&utm_medium=social&utm_campaign=killbait_es.mastodon_social

#neurociencia #psilocibina #alz...

Un caso clínico sugiere mejoras temporales en una paciente con alzhéimer tras psilocibina

Un estudio de caso realizado en Brasil ha explorado los posibles efectos de la psilocibina, el compuesto psicodélico presente en los hongos alucinógenos, en una paciente anciana con alzhéimer avanzado. La mujer, de más de 80 años, presentaba un deterioro cognitivo severo, con comunicación limitada a monosílabos, alta dependencia para las actividades básicas y pérdida de control de funciones como la vejiga. En un entorno clínico supervisado y con consentimiento legal, recibió una dosis elevada de 5 gramos de hongos con psilocibina, considerada una cantidad alta incluso en contextos recreativos. Tras esta primera administración, experimentó un estado de sueño profundo prolongado. Aproximadamente 19 horas después, comenzó a mostrar cambios conductuales relevantes, incluyendo mayor interacción verbal, mejora en la comunicación y, en los días siguientes, recuperación parcial de la autonomía en actividades como caminar, vestirse y controlar la vejiga. Estas mejoras se mantuvieron durante varias semanas de forma parcial. Un mes después recibió una segunda dosis de 3 gramos, durante la cual permaneció consciente y verbalmente expresiva, mostrando mayor emocionalidad, humor espontáneo y mejor interacción social. Sin embargo, los investigadores advierten que el estudio carece de medidas clínicas estandarizadas y monitorización neurofisiológica, por lo que no puede interpretarse como una reversión del alzhéimer. Los autores subrayan que los resultados son observacionales y que la hipótesis de una recuperación funcional temporal del cerebro requiere ensayos clínicos controlados. Actualmente, otros grupos científicos están investigando el uso de psilocibina en trastornos neurodegenerativos y depresión en personas mayores, aunque su eficacia, seguridad y dosis óptimas aún no están establecidas.

KillBait

My mom lost her sense of smell at least a decade before the worst symptoms of dementia showed up. We had no idea there was a correlation then. 😢
#alz #alzheimersanddementia #CognitiveNeuroscience #CognitiveImpairment #dementia

https://www.dailymail.co.uk/health/article-15060917/Early-senseory-symptom-dementia-years-diagnosis.html#webview=1

Researchers pinpoint new symptom which can predict dementia YEARS before diagnosis

A new study by German researchers has confirmed this new symptom is one of the earliest signs of dementia.

Daily Mail

I'm just $85 short of my goal of raising $500 for #ALZ research. You can give @ http://act.alz.org/goto/dougwhitfield

100% of your donation goes to research.

Their score is 97%! https://www.charitynavigator.org/ein/133039601

International Committee for the Red Cross is just 86%: https://www.charitynavigator.org/ein/986001029

The New Orleans Friends of Music is 83%: https://www.charitynavigator.org/ein/726021704

This is not to shame anyone, but to give some context to the Alzheimer's Association being good!

If everyone that saw this gave $5 I would be there in no time!

Douglas Whitfield is participating in the Alzheimer's Association Ride to End ALZ

I am inspired by science and driven by determination to end Alzheimer's. Donate today and help advance research toward the first survivor of Alzheimer's.

Alzheimer's Association

I'm just $85 short of my goal of raising $500 for #ALZ research. You can give @ http://act.alz.org/goto/dougwhitfield

100% of your donation goes to research.

Their score is 97%! https://www.charitynavigator.org/ein/133039601

International Committee for the Red Cross is just 86%: https://www.charitynavigator.org/ein/986001029

The New Orleans Friends of Music is 83%: https://www.charitynavigator.org/ein/726021704

This is not to shame anyone, but to give some context to the Alzheimer's Association being good!

If everyone that saw this gave $5 I would be there in no time!

Douglas Whitfield is participating in the Alzheimer's Association Ride to End ALZ

I am inspired by science and driven by determination to end Alzheimer's. Donate today and help advance research toward the first survivor of Alzheimer's.

Alzheimer's Association

The #Trump administration wants to address #chronicdisease but just cut funding to a 30-year-long diabetes study.

It found non-pharmaceutical ways to cut the likelihood of getting diabetes by 58% and now is studying #Alzheimer's + #diabetes—all priorities for RFK Jr.

Why pull the funding now? Elaine Chen
@STAT has more:

https://www.statnews.com/2025/03/17/trump-cuts-columbia-university-nih-cancels-diabetes-prevention-program-study/

#maha #health #healthcare #medicine #research #Healthpolicy #RFK #ALZ

NIH cancels funding for landmark diabetes study at a time of focus on chronic disease

The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said.

STAT

“BenfoTeam is [a] version of vitamin B1, known as benfotiamine. Researchers said early tests show it could possibly slow down or even reverse Alzheimer’s.

“This trial is for people 50-89 with mild memory concerns or mild Alzheimer’s disease. People can’t be in a long-term care facility and must be willing to participate in the full 18-month program.”

https://www.actionnews5.com/2024/09/04/clinical-trial-groundbreaking-alzheimers-disease-drug-begins-middle-tennessee/
#Alzheimers #alz #dementia

Clinical trial for groundbreaking Alzheimer’s disease drug begins in Middle Tennessee

The study is calling for participants who have mild cognitive impairment or early AD.

Action News 5
Only 14 were in this study in England but it looks really great. Benefits for those with Alzheimer's and to all, in better empathy and social engagement. The study "presents an intriguing connection between musical engagement & the cognitive function of individuals with dementia."
#alz #Alzheimers #dementia #study #England #improved #social #engagement #empathy for #patients #listening or #singing or #playing #instrument #mental #health #music #cognitive #function
https://www.psypost.org/can-prior-musical-experience-benefit-frontotemporal-dementia-patients/
Can prior musical experience benefit frontotemporal dementia patients?

A UK study found individuals with behavioral variant frontotemporal dementia who had musical experience showed better social and emotional functioning. This suggests that music might play a role in enhancing socio-emotional well-being in dementia patients.

PsyPost
What a meaningful way to spend #NationalCaregiversDay !
Thank you to Bea from @SpeakerPelosi ‘s office for meeting w/our mighty band of #ALZ advocates & caregivers. Powerful stories & empathy were shared; 2024 policy priorities discussed. #ENDALZ @AlzNorCalNorNev

A possible clue in the hunt for what exactly causes Alzheimer's: It looks like Alzheimer's might be able to be transmitted.

Based on VERY rare cases of people who had, as children, received growth hormone taken from the brains of human cadavers and later developed early-onset Alzheimer's, it looks like ALZ might be related to prion diseases like Creutzfeldt-Jakob

https://www.statnews.com/2024/01/29/first-transmitted-alzheimers-disease-cases-growth-hormone-cadavers/

#alz #AD #alzheimers #prion #dementia #health #medicine #research #MedMastodon

Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

Scientists document the first-ever transmitted Alzheimer’s cases, tied to a no-longer-used medical procedure.

STAT