Havana Syndrome (BUFFALO, NY) + Mr. [Redacted] (ATHENS, GA) // Allergic + Albuterol

South Bend Commons, Wednesday, April 8 at 07:00 PM EDT

hardcore synth punk freaks HAVANA SYNDROME on tour coming down from Buffalo ! Dancing never came easier...

and fast punx Mr. [Redacted] coming down from Athens to get in on the fun

LOCALS:

Albuterol's first show - we're talking pogo we're talking fast riffs all go no slow baby

Allergic hxc punk legends who NEVER MISS

ALL AGES - SOUTH BEND COMMONS

7PM and $7 (pay what you can)

https://atlanta.askapunk.net/event/havana-syndrome-buffalo-ny-mr-redacted-athens-ga-allergic-albuterol

So my #albuterol #inhaler now costs $30 each with my very expensive Silver level Blue Cross #insurance. It had been $0 as a generic maintenance med the last 3 years on this same plan

Meanwhile my expensive name brand Spiriva inhaler is still $0

This makes no sense

And after 15 min on the phone with the insurance co, all the nice agents in the Philippines can do is say, yep it costs $30

Oh did I mention my Emergency Room copay went from $75 to $375?
#medicalinsurance #healthinsurance #broke

I've never seen so many scripts for #albuterol as I've seen the last few years, across several different healthcare organizations... It's basically an inhaler to make it easier to breathe. I wonder if there's a national (international?) database tracking albuterol sales, and if that data has any prognostic value as an airborne vasculopathic immune depleting virus continues to spread unfettered... 🤔

{Acronym alert - glossary at bottom.} I see more #asthma patients getting bumped from ICS-only monotherapy (and/or SABA-only rescue med) to combo ICS-LABA inhalers. This is spurred by GSK discontinuing brand-name Flovent, and GINA guidelines promoting AIR and MART (aka SMART) strategy, which utilizes a combo inhaler containing formoterol, like Symbicort, Breyna, or Dulera. This is a big change for many people, who're used to using an inhaled #steroid for control and prevention, and inhaled #albuterol for rapid relief. Now they can use one inhaler for both -- which is convenient, and may bring better control.

Explainer "What is SMART Therapy for Asthma?": https://allergyasthmanetwork.org/news/asthma-smart-therapy/

Now I'm also seeing PCPs, pediatricians, and pulmonologists prescribing other combo ICS-LABA inhalers like Advair with a SMART asthma action plan -- even though that's not approved under GINA or NAEPP guidelines. In fact they explicitly warn against this: "Combination ICS with non-formoterol LABA cannot be used as-needed for symptom relief." (GINA main report, p. 69). LABAs like salmeterol (more lipophilic) take much longer to kick in (30+ minutes) to be intended for rapid relief, and have not been studied for rescue use. But they're being prescribed that way anyway, presumably due to availability, insurance coverage, and clinician confusion during a time of flux. Leading to a lot of follow-up conversations.  

GINA 2023 main report: https://ginasthma.org/wp-content/uploads/2023/07/GINA-2023-Full-report-23_07_06-WMS.pdf .

NIH NAEPP 2020 Asthma Guidelines: https://www.jacionline.org/article/S0091-6749(20)31404-4/fulltext

Glossary (in no order):

  • ICS == inhaled corticosteroid (Flovent, QVAR). Steroids reduce airway inflammation slowly over time.
  • SABA == short-acting beta-agonist: a bronchodilator (canonically albuterol) that quickly relieves airway constriction, for a few hours.
  • LABA == long-acting beta-agonist (ex: salmeterol, formoterol), relieves airway symptoms for more than a few hours.
  • Rescue med, aka "reliever" == a rapid-acting drug to relieve acute symptoms (e.g. albuterol, epinephrine).
  • Maintenance therapy == drug you take daily to prevent acute symptoms.
  • Monotherapy == managing a disease with just one drug.
  • AIR == Anti-Inflammatory Reliever: combo inhaler with a low-dose steroid + a rapid-acting bronchodilator
  • MART == Maintenance And Reliever Therapy: treatment with an inhaler that contains both a steroid and a rapid-onset, long-acting beta-agonist (formoterol). Also called SMART (S == "Single-inhaler").
  • GINA == Global Initiative on Asthma

#MedMastodon #pulmonology #pediatrics

SMART Therapy for Asthma | Allergy & Asthma Network

Learn about combination treatments in Single Maintenance and Reliever Therapy (SMART) for management of moderate to severe asthma.

Allergy & Asthma Network

Data on using #medications beyond their printed #ExpirationDates. TL;DR: the FDA requires a date at which it is guaranteed to have at least 90% of active drug. Many drugs retain full potency long past that. See article for a few specifics. #epinephrine #albuterol

(Caveat-replace your eye drops-breakdown of preservatives is no good for your eyeballs.)
#safety
Disclaimer-I’m not your doctor.

https://www.medscape.com/s/viewarticle/996754?src=FYE

More on Using Expired Medications

A patient inquires about whether they can use an EpiPen after the expiration date. What should you advise?

Medscape
Cipla Issues Voluntary Nationwide Recall of Six Batches of Albuterol Sulfate Inhalation Aerosol, 90 mcg (200 Metered Inhalation) Due to Container Defect

Cipla Limited (BSE: 500087; NSE: CIPLA EQ; and hereafter referred to as "Cipla"), today announced that its wholly-owned subsidiary Cipla US is voluntarily recalling six batches of Albuterol Sulfate Inhalation Aerosol, 90 mcg (200 Metered Inhalation) manufactured in November 2021 to the consumer leve

U.S. Food and Drug Administration

Attn: Those With #Asthma:

If you have not received your recall letter, yet: these are the #Albuterol inhaler recall lot # 's

IB20045 exp. 11/23
IB20055 exp. 11/23
IB20056 exp. 11/23
IB20057 exp. 11/23
IB20059 exp. 11/23
IB20072 exp. 11/23

I know, one more thing to deal with. Contact your pharmacy to arrange for replacement.

More info:
Cipla USA: 844 247 5287
[email protected]
1 888 INFO-FDA (888 463 6332) www.fda.gov

I have such bad shakes now that using my Trackball is almost impossible!

#Asthma #Albuterol

US liquid albuterol shortage expected to worsen after major supplier shuts down

"Albuterol is an essential critical medicine. We need robust, high-quality manufacturing of this and many other critical medicines that are produced on or near US soil." --David Margraf, PharmD, PhD

https://www.cidrap.umn.edu/resilient-drug-supply/us-liquid-albuterol-shortage-expected-worsen-after-major-supplier-shuts-down

#albuterol #fda #healthcare #PublicHealth #HealthcareForAll

US liquid albuterol shortage expected to worsen after major supplier shuts down

CIDRAP