Merely a few conditions now being pursued for secondary prevention or treatment with #GLP-1/GIP/glucagon drugs like #Ozempic or #Zepbound

Alzheimer disease
Parkinson disease
Stroke
Heart failure
CKD
MASLD/MASH
Type 2 diabetes
Sleep apnea
Psoriasis
Osteoarthritis
Substance use disorder
ALS
And more 🤗

We may be watching the emergence of an entirely new class of systems-level disease modifiers, not just “weight loss drugs.”

Longevity Cocktail based on Science 👍

Cholesterol (LDL)
-Statin (low dose rosuvastatin)
-Zetia (ezetimibe)

Gut Health
-Psyllium 10-12 gm/day

Muscle (and maybe Brain)
-Creatine

Cognitive/Biologic Aging
-Multivitamin (generic Centrum Silver)

Metabolic, Insulin Resistance, Anti-inflammatory
-Low dose Zepbound/Mounjaro (tirzepatide)

https://substance-over-noise.beehiiv.com/p/the-longevity-stack

#longevity #rosuvastatin #zetia #psyllium #creatine #Zepbound #Mounjaro #tirzepatide #cholesterol #ldl #glp1

Update: New Options for Weight Loss

The landscape of metabolic medicine is shifting beneath our feet. For the last few years, the conversation has been dominated by weekly injections like #Zepbound (#tirzepatide), #Wegovy (#semaglutide), #Foundayo (#orforglipron) and #retatrutide.

https://bit.ly/4sbhJVl
#obesity #WeightLoss

Global sugar demand stalls as health policies and weight-loss drugs curb consumption

https://fed.brid.gy/r/https://dailytimes.com.pk/1447135/global-sugar-demand-stalls-as-health-policies-and-weight-loss-drugs-curb-consumption/

WHO發布指南建議使用「GLP-1類藥物」治療成人肥胖症，2030年全球20億人過重

The finding that tirzepatide can quiet “food noise” is remarkable. Imagine having similarly precise treatments for other intrusive or compulsive mental states, like those seen across many anxiety disorders.

#GLP1
#Mounjaro
#Zepbound

https://www.nature.com/articles/d41586-025-03766-2