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Happy World Heart Day 💜
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8 Foods to Keep Your Heart Strong
8 Foods to Keep Your Heart Strong #worldheartday #heart #otvnews --------------------------------------------------------------------------------------------------------- OdishaTV is Odisha's no 1 News Channel. OTV being the first private satellite TV channel in Odisha carries the onus of charting a course that behoves its pioneering efforts. Accordingly its charter objectives are FREE, FAIR and UNBIASED. OTV delivers reliable…
Today is World Heart Day! Celebrate today by exercising and encouraging others to be more active and improve their cardiovascular health.
🫀📄 #WorldHeartDay: 'Adjunctive Left Atrial Posterior Wall Isolation in Treating Non-Paroxysmal Atrial Fibrillation: An Updated Meta-Analysis of Randomized Clinical Trials' - a systematic review in the Karger: Cardiovascular System Collection on #ScienceOpen 🔗 https://www.scienceopen.com/document?vid=77109481-17c1-4252-abd3-39d848c039ae
#AtrialFibrillation #CatheterAblation #Electrophysiology #ScienceMastodon
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7340757e137"> <b> <i>Background:</i> </b> The clinical outcomes of adjunctive posterior wall isolation (PWI) beyond pulmonary vein isolation (PVI) for non-paroxysmal atrial fibrillation (AF) remain unclear. This meta-analysis was conducted to evaluate the role of PWI in non-paroxysmal AF by pooled analysis of most updated randomized controlled trials (RCTs). <b> <i>Methods:</i> </b> A literature search in PubMed, Embase, and the Cochrane Library was performed to identify RCTs comparing the outcomes of PVI with and without PWI in non-paroxysmal AF patients. The primary outcomes were recurrence rates of all atrial arrhythmias, AF, and atrial tachycardia/flutter (AT/AFL). The secondary outcomes included total procedure time, ablation time, fluoroscopy time and procedure-related complications. Estimated risk ratios (RRs) and 95% confidence intervals (CIs) were evaluated. <b> <i>Results:</i> </b> Nine RCTs with a total of 1,243 non-paroxysmal AF patients were included in our analysis. There were no significant differences in all atrial arrhythmias recurrence (RR: 0.86, 95% CI: 0.66–1.11, <i>p</i> = 0.24, <i>I</i> <sup>2</sup> = 49%) and AF recurrence (RR: 0.74, 95% CI: 0.51–1.08, <i>p</i> = 0.12, <i>I</i> <sup>2</sup> = 62%) between stand-alone PVI group and PVI plus PWI group. Adjunctive PWI increased the AT/AFL recurrence rate (RR: 1.62 95% CI: 1.08–2.42, <i>p</i> = 0.02, <i>I</i> <sup>2</sup> = 0%). In the subgroup analysis, PWI using cryoballoon ablation was associated with a significantly lower recurrence rate of all atrial arrhythmias ( <i>p</i> = 0.01) and AF ( <i>p</i> = 0.02) recurrence and similar recurrence rate of AT/AFL ( <i>p</i> = 0.15). Additional PWI was associated with an increased AT/AFL recurrence ( <i>p</i> = 0.03) in patients with left atrial diameter (LAD) <44 mm. Adjunctive PWI needed longer ablation time, fluoroscopy time, and total procedure time. The incidence of procedural adverse events was low and similar between both groups. <b> <i>Conclusion:</i> </b> Adjunctive PWI beyond PVI did not improve the freedom from all atrial arrhythmias and AF with an increased recurrence rate of AT/AFL in non-paroxysmal AF patients. The ablation energy and LAD might affect the clinical outcome of PWI. However, larger more RCTs were needed to verify our findings. </p>
🫀📄 #WorldHeartDay: 'Electrocardiographic Strain and Relationship with Left Ventricular Remodelling and Clinical Outcomes in Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation' - a research article in the Karger: Cardiovascular System Collection on #ScienceOpen 🔗 https://www.scienceopen.com/document?vid=96c293ec-03c9-46ed-bf91-ce2b451d58b7
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7341480e220"> <b> <i>Introduction:</i> </b> Left ventricular (LV) remodelling and fibrosis are known to occur in patients with aortic stenosis (AS) and are linked to post-intervention outcomes. These myocardial changes may be detected upon the routine 12-lead electrocardiogram (ECG) by the presence of a LV strain pattern (LVS-ECG). Although LVS-ECG has been related to excessive cardiovascular morbidity and mortality in multiple patient populations, there is currently a dearth of data upon its impact in patients undergoing transcatheter aortic valve implantation (TAVI). The aim of the current study was to investigate the prevalence, predictors, and prognostic value of LVS-ECG. <b> <i>Methods:</i> </b> Between 2012 and 2019, 640 consecutive patients underwent TAVI at Haukeland University Hospital, Bergen. Of these, 600 patients with severe AS were included in the TAVI-NOR study. Patients with known bundle branch block ( <i>n</i> = 85) or permanent pacing ( <i>n</i> = 25) were excluded, leaving 490 patients (mean age 81 ± 6 years, 52% females) eligible for the analyses. LVS-ECG was defined as down-sloping, convex ST-segment depression with asymmetric T-wave inversion in V5 or V6. <b> <i>Results:</i> </b> LVS-ECG was present in 25.7% patients. Higher levels of NT-proBNP (OR 1.96; 95% CI: 1.08–3.55, <i>p</i> = 0.028), left ventricular ejection fraction (LVEF) <50% (OR 3.14; 95% CI: 1.61–6.13, <i>p</i> = 0.001), increase in LV mass index per SD (32 g/m <sup>2</sup>) (OR 1.37; 95 CI: 1.06–1.76, <i>p</i> = 0.014), and the presence of LV hypertrophy on ECG (OR 3.23; 95% CI: 1.97–5.32, <i>p</i> < 0.001) were independent predictors of LVS-ECG in the multivariable-adjusted analysis. Although all-cause mortality was significantly higher in patients with LVS-ECG compared to those without (54.8% vs. 44.2%, <i>p</i> = 0.041), the presence of LVS-ECG did not predict all-cause mortality during a mean follow-up of 64 ± 24 months (HR 1.05; 95% CI: 0.79–1.39, <i>p</i> = 0.742). Patients with LVEF <50% and concomitant LVS-ECG had a worse prognosis than those with LVEF >50% and no LVS-ECG ( <i>p</i> < 0.001). <b> <i>Conclusions:</i> </b> LVS-ECG may represent a simple marker of structural and functional LV remodelling that signals a propensity to excess mortality during long-term follow-up after TAVI, as it is strongly associated with other prognosticators such as reduced LVEF and increased levels of NT-proBNP. </p>
🫀📄 #WorldHeartDay: 'The Functional Unit of the Lymphatic System: Towards Understanding the Importance of a Well-Rehearsed Interaction of Lymphatic Capillaries, Collecting Vessels, and Lymph Nodes' - a review article in the Karger: Cardiovascular System Collection on #ScienceOpen 🔗 https://www.scienceopen.com/document?vid=6f805b1d-3f4e-4045-a4da-b35060bb05be
#LymphaticSystem #Immunology #VascularBiology #ScienceMastodon
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7349083e130"> <b> <i>Introduction:</i> </b> Lymphatic vessels and lymph nodes (LNs) are part of the lymphatic system taking care of interstitial tissue homoeostasis, lipid transport, and immune response. The interposition of LNs in between the lymphatic vasculature allows the filtration of lymph fluid, cell-cell interactions, and also the transfer of lymph fluid into the venous system. An important role of lymphatic flow, which is often underestimated, is the active involvement of lymph flow and the lymphatic vasculature in immunologic function. <b> <i>Summary:</i> </b> The present review summarizes the current knowledge of the different functional units of the lymphatic transport system trying to create a model of their interplay and options to react to inflammatory conditions. Remodelling of the lymphatic system during inflammation includes lymphangiogenesis, changed fluid transport rates, and modification of LN morphology. Alterations of these processes can aggravate inflammatory processes, leading to an incomplete resolution of the inflammation and often ending in chronic inflammatory condition. Despite the development of histological markers to visualize lymphatic vessels, new imaging methods and increased knowledge about the different parts of the lymphatic system the general overview about the interplay of the different components is missing. <b> <i>Key Messages:</i> </b> We show the importance of lymphatic flow in the initiation of the immune response and the solution of an inflammation. We speculate that the increase in density and vessel diameter of lymph vessels is necessary to increase the fluid influx, efflux and the migration of cells into the LN. A failure of antigen-tissue clearance leads to chronic inflammation. Remodelling of LN morphology and vasculature is also necessary in this reaction. An overrun of the defending capacity of the LN is prevented by the immune system via control of the lymph vessel transport capacity and LN remodelling. </p>
#DontMissABeat: It’s World Heart Day! ❤️🩹
This #WorldHeartDay, we highlight the Cardiovascular System Collection from Karger Publishers on #ScienceOpen — featuring cutting‑edge research in basic and clinical #Cardiology, #VascularBiology, #CardiorenalMedicine, and more.
📚 https://www.scienceopen.com/collection/Karger_CardiovascularSystem
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