Giuseppe Michieli#Epidemiological and #virological #update on the emerging #SARS-CoV-2 #variant BA.3.2, https://etidiohnew.blogspot.com/2025/11/epidemiological-and-virological-update.html
Identification of #clinical and #virological correlates associated with #influenza A candidate #vaccine virus (#CVV) attenuation in a #ferret model, https://etidiohnew.blogspot.com/2025/09/identification-of-clinical-and.html
#Virological characteristics of the #SARS-CoV-2 #NB181 #variant, https://etidiohnew.blogspot.com/2025/06/virological-characteristics-of-sars-cov.html
#Antigenic and #virological characteristics of #SARS-CoV-2 #variants BA.3.2, #XFG, and #NB181, https://etidiohnew.blogspot.com/2025/06/antigenic-and-virological.html
Identification & #genetic & #virological characterisation of a #human case of avian #influenza A #H9N2 virus from Eastern #India, https://etidiohnew.blogspot.com/2025/05/identification-genetic-virological.html
[Correspondence] #Virological characteristics of the #SARS-CoV-2 #LP.8.1 #variant https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00079-9/fulltext?rss=yes
LP.8.1 (JN.1.11.1.1.1.3.8.1), a descendant lineage of KP.1.1.3 (JN.11.1.1.1.3), is starting to spread worldwide. LP.8.1 has acquired nine spike protein mutations compared with JN.1, and eight amino acid residues differ between the spike proteins of LP.8.1 and XEC.
[Correspondence] #Virological and #antigenic characteristics of #SARS-CoV-2 #variants #LF.7.2.1, #NP.1, and #LP.8.1 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00015-5/fulltext?rss=yes
... several sublineages of #JN.1 are increasingly out-competing XEC and KP.3.1.1, exhibiting superior growth advantages; for example, LF.7.2.1, MC.10.1, NP.1, and, most importantly, LP.8.1 (figure A, B).
#Virological characteristics of the #SARS-CoV-2 #XEC #variant
Source: Lancet Infectious Diseases, Correspondence, {Excerpt} Altogether, here we showed that XEC exhibited higher pseudovirus infectivity and higher immune evasion than KP.3. Particularly, XEC exhibited more robust immune resistance to KP.3.3 BTI sera than KP.3.1.1. Our data suggest that the higher Re of XEC than KP.3.1.1 is attributed to this property and XEC will be a predominant SARS-CoV-2 variant in the…
https://etidioh.wordpress.com/2024/11/07/virological-characteristics-of-the-sars-cov-2-xec-variant/
#Virological #characteristics of the #SARS-CoV-2 #KP311 #variant http://biorxiv.org/cgi/content/short/2024.07.16.603835v1?rss=1
KP.3.1.1 exhibited a higher Re, higher pseudovirus infectivity, & higher neutralization #evasion than KP.3. These results align with our recent report that #JN1 subvariants with S:S31del (eg KP.2.3 & LB.1) exhibited enhanced Re and immune evasion compared to other JN.1 subvariants without S:S31del (eg JN.1, KP.2, & KP.3), highlighting evolutionary significance of S:S31del in JN.1 lineages.
#Virological characteristics of the #SARS-CoV-2 #KP3, #LB1, and #KP23 #variants, Lancet Infect Dis.: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00415-8/fulltext?rss=yes
JN.1 subvariants such as LB.1 (JN.1.9.2.1) and KP.2.3 (JN.1.11.1.2·3), which convergently acquired a deletion at the 31st position in S (Ser31del) in addition to the aforementioned substitutions, have emerged and spread as of June, 2024 (appendix pp 12–13).