๐—ช๐—ผ๐—ฟ๐—น๐—ฑ ๐—”๐—œ๐——๐—ฆ ๐—ฉ๐—ฎ๐—ฐ๐—ฐ๐—ถ๐—ป๐—ฒ ๐——๐—ฎ๐˜† โ€“ ๐— ๐—ฎ๐˜† ๐Ÿญ๐Ÿด, ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ

Today, we recognize the ongoing fight against HIV/AIDS and the urgent need for a safe and effective vaccine. World AIDS Vaccine Day honors the dedication of scientists, healthcare workers, volunteers, and advocates striving to end this global epidemic.

Despite advances in treatment, nearly 40 million people live with HIV worldwide, with over a million new infections every year. A vaccine remains crucial for lasting protection and to ultimately eliminate HIV/AIDS.

Letโ€™s raise awareness, support research funding, and promote equitable access to future vaccines. Together, we can build hope for a future free of AIDS.

#WorldAIDSVaccineDay #HIVAIDS #EndAIDS #HIVAwareness #VaccineResearch #GlobalHealth #FightHIV #HealthForAll #ScienceMatters #HopeForAIDS #SCABPharmacy

How on earth did this pass CDC review despite multiple internal concerns? Where did scientific integrity go in the US? #PublicHealth #HepatitisB #Science #ResearchEthics #CDC #VaccineResearch #USPol

New Documents Reveal a Controv...
New Documents Reveal a Controversial Vaccine Studyโ€™s Unusual Path to CDC Approval

A new investigation has found irregularities in the ethics review of a grant to study effects of a birth dose of hepatitis B vaccine in Guinea-Bissau.

Rolling Stone

'Humoral Immune Response to #OrientiaTsutsugamushi Infection: Recent Research Findings and Future Studies' - a #Zoonoses published article on #ScienceOpen ๐Ÿ“„๐Ÿ”“๐Ÿ–‡๏ธ #HumoralImmunity #VaccineResearch

Orientia tsutsugamushi (Ot), an intracellular bacterium in the family Rickettsiaceae, is the etiological agent of #ScrubTyphus. ๐Ÿ”Ž https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2025-0020

Humoral Immune Response to <i>Orientia tsutsugamushi</i> Infection: Recent Research Findings and Future Studies

<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d10472214e156"> <i>Orientia tsutsugamushi</i> ( <i>Ot</i>), an intracellular bacterium in the family Rickettsiaceae, is the etiological agent of scrub typhus. Understanding of the immunologic responses to <i>Ot</i> infection, particularly immunity after infection, has remained a major knowledge gap. Although anti- <i>Ot</i> IgG appears to be short-lived in infected humans, recent studies have reported autoreactive IgM antibodies in people with scrub typhus, including antibodies reactive to nuclear components, DNA, and platelets. However, mechanistic studies of B cell responses in the secondary lymphoid organs of infected humans are severely lacking. This article highlights feasible methods to investigate important aspects of humoral immunity, and avenues to obtain samples from post-mortem and ante-mortem <i>Ot</i>-infected people. A pioneer study identified that serum passive transfer could protect against homologous Ot challenge. Studies comparing humoral immune responses to <i>Ot</i> Karp versus Gilliam strains have revealed impaired B cell and germinal center (GC) responses during severe, but not self-limiting, infection in C57BL/6 mice. Further studies are needed, particularly in people with scrub typhus, to help understand and define deficiencies in the acute B cell response and long-lived humoral immunity. </p>

ScienceOpen
We are back to the dangers that will be unleashed because of the foolhardy decisions of a few. The entire healthcare, academic and life sciences industry in the US is in turmoil and clinical trials, pharmaceuticals and general practitioners are going to be decimated. It's almost as if the last half-decade of covid never happened! Dismantling of the Office of Pandemic Preparedness and Response Policy, cutting funding to NIH, it's the same playbook that got us into this mess. Of course, all of us in the know saw this coming and it's playing out exactly as expected. I will no longer participate or sacrifice a drop of sweat, blood or tears. We've lost too many good people, family, friends, time with loved ones and ourselves.
It was all lies and propaganda until the people making these decisions started dying... Even on their death beds they thought horse medication would save them. You cannot rationalize or have useful conversation with the clinical definition of an idiot. The laws, rules and regulations that protect the US, managed and put forth by our elected officials based on the people are all effectively dead. I'm not so naive to believe this wasn't always the plan but now that we are here, it should be obvious to anyone, we are on our own. It's time we all started acting that way.
https://www.ft.com/content/40bcb370-05da-4822-bb6c-3ea7c29f2fad
#oppr #nih #lifesciences #healthcare #cdc #apha #VaccineResearch #vaccines
US health agency leadership turmoil gives Robert Kennedy the upper hand

Battle for control of the CDC follows rising tension over health secretaryโ€™s position on vaccines

Financial Times
West Africa: Strengthening Lassa Fever Vaccine Research and Trial Capacity in West Africa: [Nigeria Health Watch] In West Africa, Lassa fever remains a persistent and recurring health threat, causing hundreds of lives each year and underscoring urgent need for sustained investment in research and vaccine manufacturing capacity. In the first five months of 2025 alone, Nigeria reported over 717 confirmed casesโ€ฆ http://newsfeed.facilit8.network/TMTWss #LassaFever #VaccineResearch #PublicHealth #WestAfrica #Nigeria

Imagine: algorithms continuously sampling pathogens, tracking evolution, synthesizing vaccines. Autonomous underground & space labs experimenting with alternative evolution. Robots creating personalized medicines!

#FutureScience #PersonalizedMedicine #SpaceLabs #VaccineResearch #AIHealth

๐Ÿ“ข Our May newsletter is now online! This month we're focusing on the value of #PPPs to address #HealthChallenges. Discover:
โœ… Draft texts for call 11
โœ… Info webinars on call 11
โœ… New project INTERCEPT
โœ… Project results for #ClinicalTrials, #PaediatricResearch and #VaccineResearch
๐Ÿ‘‰ https://europa.eu/!6mvTjP #IHITransformingHealth #HealthResearch
IHI Newsletter | Spotlight on the value of PPPs

IHI Innovative Health Initiative

[5] Then there is the #money portion of this debate. They want to strip #VaccineResearch away from the public. They claim its to better direct resources. We know that is a lie. This is shown by their recommendation that only 'high risk' individuals be vaccinated. In my previous post we established this is counter to the goal of 'evidence based public health'. By vaccinating a small proportion of the population, we do very little to move the needle. The enemy is transmission at a population scale.

If you want to know the effect of this policy, take a look at how #healthinsurance companies decide what and what not to cover (8) This recommendation will lead to #insurancecompanies dropping vaccinations (8). Fun side fact, many people assert vaccines are a money laundering scam and big pharma wants you to get vaccinatied to rake in the cash. However, vaccines actually end up hurting the pharmaceutical industry's business model (9, 10, 11)

๐ŸŒ ๐—ช๐—ผ๐—ฟ๐—น๐—ฑ ๐—”๐—œ๐——๐—ฆ ๐—ฉ๐—ฎ๐—ฐ๐—ฐ๐—ถ๐—ป๐—ฒ ๐——๐—ฎ๐˜† | ๐— ๐—ฎ๐˜† ๐Ÿญ๐Ÿด, ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ ๐ŸŒ

Today we recognize the critical need for a safe and effective HIV vaccine to end the global HIV/AIDS epidemic. Since 1997, this day honors the relentless efforts of scientists, healthcare workers, advocates, and volunteers worldwide.

๐Ÿ”น๐—ช๐—ต๐˜† ๐—ถ๐˜ ๐—บ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ๐˜€:
- Raises awareness about HIV/AIDS and prevention
- Honors those working tirelessly on vaccine research
- Calls for increased funding and support
- Promotes equitable access to future vaccines
- Inspires hope for a world without AIDS

๐Ÿ”น ๐—ฃ๐—ฟ๐—ผ๐—ด๐—ฟ๐—ฒ๐˜€๐˜€ ๐—ถ๐—ป ๐—›๐—œ๐—ฉ ๐˜ƒ๐—ฎ๐—ฐ๐—ฐ๐—ถ๐—ป๐—ฒ ๐—ฟ๐—ฒ๐˜€๐—ฒ๐—ฎ๐—ฟ๐—ฐ๐—ต ๐—ถ๐—ป๐—ฐ๐—น๐˜‚๐—ฑ๐—ฒ๐˜€:
- Broadly Neutralizing Antibodies (bNAbs)
- T Cell Immunity approaches
- mRNA vaccine technology
- Mosaic Immunogens combining multiple HIV strains

Despite advances in treatment, millions still live with HIV, and new infections continue. A vaccine remains essential to truly control and end the epidemic.

Letโ€™s unite to support research and educate communities worldwide.

#WorldAIDSVaccineDay #HIVVaccineAwareness #EndAIDS #HIVPrevention #VaccineResearch #GlobalHealth #StopHIVAIDS #HopeForACure #HealthcareHeroes #SCABPharmacy #TogetherForAIDSFreeFuture

๐Ÿ’ก Today is the first day of #WorldImmunizationWeek, and
we're shining the spotlight on the VITAL project, which recently released two tools to help promote #VaccineUptake amongst the elderly ๐Ÿ‘ต๐Ÿ‘ด
๐Ÿ‘‰ Read more: https://europa.eu/!GJq8T8
#IHITransformingHealth #VaccineResearch
Promoting vaccination amongst the elderly with VITALโ€™s new tools

The VITAL project published an educational platform as well as a toolbox to boost vaccination uptake amongst older people.

IHI Innovative Health Initiative