An out-of-Africa story hiding in our DNA

"Who are we and where do we come from?" This quintessential question has intrigued humanity for millennia. Currently, the "Out-of-Africa (OOA) theory" is prevailingly accepted regarding the origin of modern humans, as a line of evidence indicates that Homo sapiens originated in Africa.

This protein is most frequently discussed for its role in obligate hibernator mammal brown fat. It is localized in the mitochondrial inner membrane and it functions when the animal is being roused from hibernation, shutting down ATP production in mitochondria, channeling the energy produced by the organelle into heat instead. In non-hibernating mammals its role is a little mysterious.

Human & mouse uncoupling protein 1 (#UCP1:p | #SLC25A7:p)―GPMDB tissue tabbulations #proteomics #uncoupling