The virus nearly everyone has and its possible role in MS | The-14

Nearly everyone carries Epstein-Barr virus, but research suggests it may trigger multiple sclerosis, opening new paths for prevention and treatment.

The-14 Pictures
How vaccines give our immune systems a home advantage | The-14

How vaccines train our immune system’s front-line and adaptive defenses, building lasting protection and giving the body a crucial home advantage.

The-14 Pictures

The cell that saves your life every day

https://tube.blueben.net/w/pgTpXsH9Lo7cCGAZNAhV8f

The cell that saves your life every day

PeerTube
2026 Angerer Alm T Cell Summit with T Cell Connect Europe (EFIS-IL). Great discussions on T cell biology and immunotherapy. #Immunology #TCells #EFIS #Networking
For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human #immune cell—known as helper T cells—from stem #cells in a controlled laboratory setting.
#Biomedical #Bioengineering #Tcells #sflorg
https://www.sflorg.com/2026/01/bmed01082601.html
Stem cell engineering breakthrough paves way for next-generation living drugs

UBC researchers discover how to grow specialized immune cells for more accessible off-the-shelf cell therapies to treat cancer, autoimmune disorders

Discovery of cells that keep immune responses in check wins medicine Nobel Prize https://arstechni.ca/9CPF #tregulatorycells #immunesystem #Health #tcells #nobel
Discovery of cells that keep immune responses in check wins medicine Nobel Prize

Their work revealed a peripheral mechanism that keeps immune system from causing harm.

Ars Technica

🔬 The Quiet Revolution: When Medicine Learns to Remember

What if borrowed immune cells could save immunocompromised lives?

TVGN489 trial results are paradigm-shifting.

Cancer patients cleared COVID in 4 days. The donor cells stayed active for 6 MONTHS—defying everything we thought we knew about rejection.

This isn't just about COVID. It's about shared immunity as community care.

🎧 Listen: https://www.buzzsprout.com/2405788/episodes/405788

📖 Essay: https://helioxpodcast.substack.com/publish/post/74853743

14 min • S5 E39 • Heliox: Where Evidence Meets Empathy

#COVID19 #CellularTherapy #Immunology #MedicalResearch #LongCOVID #Immunocompromised #TCells #HealthScience #Podcast #Medicine

#Psoriasis may be effectively cured by early antibody therapy. Ongoing study. #Immunesystem #Tcells
https://www.nature.com/articles/d41586-025-02649-w
A psoriasis cure could be in touching distance

Today’s antibody therapies must be taken for life to avoid severe setbacks. Researchers are pushing for a more durable treatment.

📢 Call for speakers

We are looking for early-career researchers to speak in FocalPlane's mini-symposium run together with the popular membrane trafficking webinar series organised by Francesca Bottanelli, Fèlix Campelo and Ishier Raote.

Application deadline: Sunday 24 August

Find out more:

https://focalplane.biologists.com/2025/07/14/focalplane-features-membrane-trafficking-apply-to-give-a-talk/

#FocalPlaneFeatures #Microscopy #MembraneTrafficking #Cells #TCells #ECR #ImmunologicalSynapse #MembraneDynamics #Microscope #CellBiology

'Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia' - a Genes & Diseases article on #ScienceOpen:

🔎 https://www.scienceopen.com/document?vid=a1a783a1-5180-487b-b736-d5d814a5fb75

#CancerImmunology #LeukemiaResearch #TCells #SingleCellSequencing

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d9200406e246">The immune microenvironment plays an important role in leukemia treatment. However, a specific single-cell profiling of the immune alteration in bone marrow of chronic myeloid leukemia (CML) patients is still lacking. We performed multi-level single-cell sequencing to systematically decipher the bone marrow T cell atlas of CML patients. The results exhibited extensive changes of T cells, including the decreased CD4 T cells and increased CD8 T cells in the CML bone marrow. Subpopulation analysis revealed a significant increase of CD8 terminal effector (TE) cells and a significant decrease of CD4 naïve T cells. T cell receptor sequencing showed that the overall diversity of the T cell receptor repertoire was reduced in CML, with the exception of the CD8 TE cell. In addition, CD8 TE cells were the main source of gene expression differences in CD8 T cells. Intercellular communication analysis revealed the altered interaction between CD8 TE and other non-T cells in CML, including neutrophil subtype, indicating the potential regulation of bone marrow microenvironment cells on CD8 TE dynamics. Collectively, our work characterises the alteration of T cell subsets in CML patients at multiple single-cell levels, providing a valuable resource for understanding the immune microenvironment and developing new immune strategies for CML therapy. </p>

ScienceOpen