Mastodawn

Alkyl Swap is a novel chemical methodology that allows scientists to directly edit complex molecules by replacing specific methyl groups, bypassing the need to reconstruct the entire molecule from scratch.
#OrganicChemistry #SyntheticChemistry #Pharmacology #sflorg
https://www.sflorg.com/2026/06/chm06152601.html

The Future of Molecular Editing

Discover how the Alkyl Swap method allows chemists to directly edit N-methylamines under mild conditions, accelerating modern drug research.

Scientific Frontline May 21

Researchers have successfully synthesized and stabilized rare radical anions containing an extended four-atom nitrogen chain
#SyntheticChemistry #ComputationalChemistry #AtmosphericChemistry #sflorg
https://www.sflorg.com/2026/05/chm05212602.html

Rare Four-Nitrogen Chain Anions Synthesized

Scientists successfully synthesized and stabilized rare four-atom nitrogen chain radical anions, unlocking new high-energy material applications.

Scientific Frontline May 19

A novel synthesis method that utilizes "cation sampling" to guide positive charges along molecular chains, allowing for the precise modification of previously hard-to-reach carbon-hydrogen (C–H) bonds.
#OrganicChemistry #SyntheticChemistry #Chemistry #sflorg
https://www.sflorg.com/2026/05/chm05192601.html

Controlling chemical reactions more efficiently and sustainably

Discover how cation sampling enables the precise, sustainable modification of C-H bonds, revolutionizing synthetic chemistry without complex catalysts

Scientific Frontline Apr 15

Researchers have achieved the first successful chemical synthesis of bacteriochlorophyll a, an infrared-light-absorbing photosynthetic pigment found in bacteria. This complex, disc-shaped macrocycle is central to microbial photosynthesis.
#SyntheticChemistry #Biochemistry #EnergySciences #sflorg
https://www.sflorg.com/2026/04/chm04152601.html

Researchers Synthesize Photosynthetic Molecule Found in Bacteria

The work represents the first chemical synthesis of this molecule and could give scientists deeper insights into photosynthetic function and photosynt

Hacker News Mar 1

Aromatic 5-silicon rings synthesized at last

https://cen.acs.org/materials/inorganic-chemistry/Aromatic-5-silicon-rings-synthesized/104/web/2026/02

#HackerNews #Aromatic #5-silicon #rings #synthesized #at #last #aromaticchemistry #siliconrings #materialsinnovation #syntheticchemistry #sciencebreakthrough

Aromatic 5-silicon rings synthesized at last

2 groups working independently construct the same long-sought compound via different routes

Chemical & Engineering News

ScienceOpen Aug 22, 2025

🔁📄 'Repositioning antivirals against COVID-19: Synthetic pathways, mechanisms, and therapeutic insights.' - a #DrugRepurposing Research article on #ScienceOpen:

➡️ https://www.scienceopen.com/document?vid=86a9a26d-fa33-4c20-8ef2-41c90ddc56fa

#REPO4EU #COVID19Research #Antivirals #MedicinalChemistry #SyntheticChemistry

Repositioning antivirals against COVID-19: Synthetic pathways, mechanisms, and therapeutic insights.

<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d6481623e211">The pandemic of COVID-19 has ignited a global race to locate effective therapies with drug repositioning emerging as a leading strategy due to its cost-effectiveness and established safety profiles. Remdesivir, Favipiravir, Hydroxychloroquine, and Chloroquine have been the focus of rigorous clinical trials to determine their therapeutic potential against SARS-CoV-2. This article delves into the innovative synthetic strategies behind these drugs, providing a blueprint for researchers navigating the complex landscape of antiviral development. Beyond synthesis, we explore the fascinating mechanisms of action: hydroxychloroquine and chloroquine elevate lysosomal pH to impede autophagy and viral replication; favipiravir, a nucleoside analogue, induces lethal mutagenesis or RNA chain termination and remdesivir disrupts viral RNA synthesis through delayed chain termination. By merging synthetic methodologies with mechanistic insights, this article offers a comprehensive resource aimed at accelerating the development of potent COVID-19 therapies and underscores the crucial part that chemistry in addressing global health emergencies. It also underscores the vital function of chemistry in addressing global health emergencies and highlights how innovative drug design and repurposing can provide rapid responses to emerging infectious diseases. This fusion of chemistry and virology not only advances our understanding of drug action but also paves the way for the discovery of new therapeutic agents crucial in future pandemics. </p>

ScienceOpen

Beilstein-Institut Jul 23, 2025

Starting tomorrow 📅 July 24, 2025 at 🕓 4 pm CEST‬: Online #BeilsteinTalk "New electrophiles, strategies, and catalysts for cross-electrophile coupling" with Daniel Weix from the University of Wisconsin-Madison.

Participation is FREE – just register 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-new-electrophiles-strategies-and-catalysts-for-cross-electrophile-coupling/?M=y

#catalyst #SyntheticChemistry #SyntheticOrganicChemistry #BeilsteinTalks

Beilstein-Institut Jul 17, 2025

Join the #BeilsteinTalk "New electrophiles, strategies, and catalysts for cross-electrophile coupling" with Daniel Weix from the University of Wisconsin-Madison on 📅 July 24, 2025 🕓 4–5 pm CEST.

Participation is FREE – just register 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-new-electrophiles-strategies-and-catalysts-for-cross-electrophile-coupling/?M=y

#catalyst #SyntheticChemistry #SyntheticOrganicChemistry #BeilsteinTalks

Beilstein-Institut Jul 10, 2025

Save the date 📅 July 24, 2025 🕓 4–5 pm CEST

Online #BeilsteinTalk "New electrophiles, strategies, and catalysts for cross-electrophile coupling" with Daniel Weix from the University of Wisconsin-Madison.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-new-electrophiles-strategies-and-catalysts-for-cross-electrophile-coupling/?M=y

#catalyst #SyntheticChemistry #SyntheticOrganicChemistry #BeilsteinTalks

Ele Willoughby, PhD Mar 12, 2024

Happy birthday to chemist William Henry Perkin (1838-1907)! This #lino print ‘William Henry Perkin Discovers Mauve’ is about how the British chemist & entrepreneur made the serendipitous discovery of the 1st synthetic organic dye: mauveine. ⁠
⁠
Perkins entered the Royal College of Chemistry in London in 1853 when he was only 15, studying with August Wilhelm von Hofmann. 🧵1/n
#linocut #printmaking #sciart #chemistry #syntheticChemistry #dye #histstm #chemist #FashionHistory #histchem #MastoArt