Jim RoseApr 21

New preprint! Which segmentation algorithm should you use for image-based spatial transcriptomics — and does the answer change by tissue?

Preprint: https://www.biorxiv.org/content/10.64898/2026.04.16.718947v1

#SpatialBiology #Bioinformatics #computationalbiology #OpenScience

Scientific FrontlineApr 1
Researchers have comprehensively mapped the microenvironment of neuroblastoma, a highly lethal pediatric cancer, discovering that the tumors utilize surrounding immune cells as "bodyguards" and specific proteins as "shields" to evade natural cell death.
#Pediatric #Oncology #MolecularBiology #SpatialBiology #sflorg
https://www.sflorg.com/2026/04/ongy04012601.html
Shields and bodyguards: scientists uncover the hidden defences of a deadly childhood cancer

Neuroblastoma accounts for approximately 10 percent of all pediatric cancer deaths

Brent StockwellJan 13
I’m pleased to announce that I’m serving as Editor in Chief of a new journal focused on #spatialbiology called EXO - Beyond the Cell. We have assembled a world-class editorial board. My deepest thanks to the outstanding scientists who have agreed to help guide EXO. no subscription fees — all papers immediately available worldwide. No author publication charges until at least 2030. (Very helpful with the new NIH policy) Rapid and concise reviews. High quality reviewers.
https://www.sciexplor.com/articles/EXO.2026.0001
EXO - Beyond the Cell, a journal about how cells interact with their environment

Show threadAlbert Vilella, PhD.Nov 5, 2025
More on #SingleCell #SpatialBiology #NGS #Multiomics at Rhymes with Haystack, albertvilella.substack.com
Rhymes with Haystack | Albert | Substack

Biotech, Next Generation Sequencing, Single cell and Spatial Biology, Next Generation Proteomics, Synthetic Biology, Small Molecules and Biologics pharma, and related topics. Click to read Rhymes with Haystack, a Substack publication with thousands of subscribers.

Albert Vilella, PhD.Nov 5, 2025
#M&A season in #SingleCell and #SpatialBiology Curio Bio -> Takara Scale -> 10X Genomics $TXG Fluent -> Illumina $ILMN Parse -> Qiagen $QGEN being the latest to be announced.
Show threadMing 'Tommy' TangOct 22, 2025
more information: https://spartaaaai2026-workshop.github.io/SPARTA_AAAI_workshop_2026/
#aaai2026
#spatialbiology #biologicalreasoning
SPARTA — Spatial Reasoning and Therapeutics with AI : From Omics to Imaging

Albert Vilella, PhD.Sep 29, 2025
Interesting publication comparing @10xgenomics.bsky.social Xenium versus @brukercorporation.bsky.social GeoMx #spatialomics #SpatialBiology

RE: https://bsky.app/profile/did:plc:mzm7vvbpjaqrhdzyk6ipu4rj/post/3lzvicmzeu22m
Albert Vilella, PhD.Sep 9, 2025
A few more #SingleCell and #SpatialBiology methods have been published recently, making it a total of 362 in the table I compiled over the years. lookerstudio.google.com/reporting/c3...
EPFL Center for ImagingJun 12, 2025
🧬🔬 Millions of molecules automatically detected in human tissues thanks to Spotiflow, a revolutionary AI-powered microscopy tool developed at
@EPFL
and
@tudresden_de
👇
📍Supported by
@EPFL_Imaging

🔗https://actu.epfl.ch/news/in-the-blink-of-an-ai-spotting-millions-of-molecul/
#AI #Microscopy #SpatialBiology #OpenScience #EPFL
In the blink of an AI: Spotting millions of molecules inside us

Scientists at EPFL and TU Dresden have developed a new machine learning method called Spotiflow that can automatically process both 2D and 3D microscopy images with unprecedented speed and precision.

Albert Vilella, PhD.Apr 14, 2025
I've added @rongfan8.bsky.social 's Lab spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq to the list of #SingleCell and #SpatialBiology #methods #SingleCell #Spatial #Method bit.ly/scmethodstable