Roberto von ArchimboldiThis is a fascinating analysis about the decline of pubs and what can be done about it.
https://laurenleek.substack.com/p/britain-lost-14000-third-places-they
If I have understood it correctly, it is rent. Not quite in the straightforward way that landlords are being charged too much rent to make the business profitable, though there is that. Instead, the ultimate owners are really property developers. They load up the pubs with debt to finance their purchase. When the pub can't pay the debt, they flip it for more rentable land use, ie property development. It is the financialisation of land that is once again at issue.
Centre for Population ChangeIn the latest issue of Changing Populations, we report on a study by CG member Dr Jo Hale from the University of St Andrews, which has found that reducing social isolation protects the brain in later life.
Head to section 8 to find out more: https://sway.cloud.microsoft/WzAYgcw05ELXCdXJ?ref=Link
#ageing #cognition #socialisolation #loneliness #brainhealth #publichealth #gerontology #Alzheimers #demography #mentalhealth #laterlife #StAndrews #healthyageing #neuroscience #wellbeing
CD CastilloLa oxitocina tiene efectos distintos dependiendo de que neuronas la liberen (NPV posterior, NPV anterior, extensión amigdalina, etc) y en que patrón lo hagan (el patrón electrofisiológico de las neuronas es muy distinto!!)
https://www.nature.com/articles/s41386-026-02352-y
#Oxytocin #Anxiety #Socialisolation #SocialAffiliation #Neurophysiology #Hypothalamus #Neuropeptides
https://www.nature.com/articles/s41386-026-02352-y
#Oxytocin #Anxiety #Socialisolation #SocialAffiliation #Neurophysiology #Hypothalamus #Neuropeptides
Oxytocin neurons in the anterior and posterior paraventricular nucleus have distinct behavioral functions and electrophysiological profiles - Neuropsychopharmacology
Oxytocin is a neuropeptide that can promote or inhibit affiliative social behaviors. Recent evidence suggests that these diverse effects are mediated by distinct oxytocin receptor-expressing neurons. An outstanding question is whether these behavioral effects are also driven by distinct or overlapping populations of oxytocin-producing neurons. The paraventricular nucleus (PVN) of the hypothalamus is a major source of oxytocin and sends projections to the mesolimbic dopamine system and extended amygdala. Previous work found that social defeat stress increased oxytocin neuron activity in the anterior PVN (aPVN) but not posterior PVN (pPVN). We reduced oxytocin synthesis with antisense morpholino oligonucleotides in either anterior or posterior PVN in California mice (Peromyscus californicus), a strong model system for studying effects of social stress on brain function and behavior. Antisense morpholinos in aPVN had no effect on behavior in unstressed females but increased social approach and reduced social vigilance in females exposed to social defeat stress. In pPVN, antisense morpholinos reduced social approach in unstressed male and female California mice. We then used OxtCre mice to compare electrophysiological profiles of oxytocin in aPVN and pPVN with a population of oxytocin neurons in the bed nucleus of the stria terminalis (BNST). Oxytocin neurons in aPVN and BNST had higher post-synaptic events and responded more strongly to current injections than oxytocin neurons in pPVN, though they had similar excitatory and inhibitory input balance at the observed resting membrane potential. These findings shed light on to functional and physiological heterogeneity of PVN oxytocin neurons. Our results suggest that context-dependent behavioral effects of oxytocin are mediated by different populations of oxytocin neurons.
Chris Geoghooligan ✊If ever there was a group that piqued my interest... alas, it's on #facebook, key enabler of #fascisim, #genocide, #hatespeech, mis- and dis-information, #surveillancecapitalism, and #socialisolation, to name a few.
Nope.
Biohacking Pathway
CapitalmindA stark new report highlights the risks of #CannabisUseDisorder, noting it affects ~20% of those who try it. For daily users in their 20s & 30s, the addiction can cause severe social withdrawal, career stagnation & eroded #MentalHealth, flipping from relief to a worsening trap. The call is for targeted awareness & cessation support. #WeedAddiction #PublicHealth #SocialIsolation
Able ChannelDid you know isolation can impact cognitive functioning? Watch out for subtle signs like difficulty keeping track of appointments or learning new tasks. Let's stay connected and support each other!
Watch full episode at https://shorturl.at/B1lEh
#MentalHealthMatters #SocialIsolation #CognitiveFunctioning
Watch full episode at https://shorturl.at/B1lEh
#MentalHealthMatters #SocialIsolation #CognitiveFunctioning
Did you know that isolation can negatively impact your brain health? Research shows that those who are socially isolated or experience loneliness may have a higher risk of developing dementia and declining cognitive performance.
Watch now at https://shorturl.at/B1lEh
#BrainHealth #MentalWellness #SocialIsolation
Watch now at https://shorturl.at/B1lEh
#BrainHealth #MentalWellness #SocialIsolation
Victoria Stuart 🇨🇦 🏳️⚧️🇨🇦 Vancouver #DTES - As cost of living climbs, a Vancouver shelter adapts to a rise in unhoused seniors
https://www.cbc.ca/news/canada/british-columbia/vancouver-seniors-homeless-shelter-9.7023974
video ( #UGM ) Vancouver homeless shelter adapting to rise in seniors
https://www.cbc.ca/player/play/video/9.7024369
#Vancouver #seniors #OlderAdults #poverty #SocialIsolation #homelessness
Reducing #socialisolation protects the #brain in #laterlife, finds Connecting Generations member Dr Jo Mhairi Hale from the University of St Andrews in a new study
Read more... 👇
https://news.st-andrews.ac.uk/archive/reducing-social-isolation-protects-the-brain-in-later-life/
Reducing social isolation protects the brain in later life
Reducing social isolation protects the brain in later life . Pathological cognitive decline is most often driven by Alzheimer’s and related dementias The study, published today (16 December 2025) in The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences found a consistent pattern of higher social isolation causing faster cognitive decline whether or not people identify as lonely. Social isolation is objectively measured