India has launched BIRSA 101, the nationโ€™s first indigenous CRISPR-based gene therapy for Sickle Cell Disease, marking a major leap in genomic medicine and affordable healthcare. https://english.mathrubhumi.com/lifestyle/health/india-crispr-gene-therapy-sickle-cell-disease-n4em93uz?utm_source=dlvr.it&utm_medium=mastodon #SickleCellDisease #CRISPRIndia #Birsa101 #GenomicMedicine
Osteomyelitis in Sickle Cell Disease Flashcard โ€” Key Pathogens and Mechanisms

Learn why Salmonella and Staphylococcus aureus are major causes of osteomyelitis in sickle cell disease. High-yield topic for USMLE Step 1.

mymedschool.org

NHS alert over often symptomless 'trait' that may be serious if inherited by children

https://fed.brid.gy/r/https://www.mirror.co.uk/news/health/nhs-alert-over-often-symptomless-35996293

๐—ช๐—ผ๐—ฟ๐—น๐—ฑ ๐—ฆ๐—ถ๐—ฐ๐—ธ๐—น๐—ฒ ๐—–๐—ฒ๐—น๐—น ๐——๐—ฎ๐˜† โ€“ ๐Ÿญ๐Ÿต ๐—๐˜‚๐—ป๐—ฒ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ

๐—ง๐—ต๐—ฒ๐—บ๐—ฒ: Global Action, Local Impact: Empowering Communities for Effective Self-Advocacy

๐—ช๐—ต๐˜† ๐—œ๐˜ ๐— ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ๐˜€:
Sickle cell disease (SCD) affects over 300,000 births globally every year, with a large burden in low- and middle-income countries like India. It disproportionately impacts marginalized communities, especially tribal populations who face socioeconomic challenges. Awareness and early diagnosis are crucial to reduce complications and improve quality of life.

๐—”๐—ฏ๐—ผ๐˜‚๐˜ ๐˜๐—ต๐—ฒ ๐——๐—ฎ๐˜†:
World Sickle Cell Day was established by the United Nations in 2008 to spotlight sickle cell disease as a major genetic health concern. The day promotes public education, encourages screening, and supports affected individuals and families worldwide.

๐—ž๐—ฒ๐˜† ๐—ฃ๐—ผ๐—ถ๐—ป๐˜๐˜€ ๐˜๐—ผ ๐—ฆ๐—ต๐—ฎ๐—ฟ๐—ฒ:
- Sickle cell disease is a genetic blood disorder causing abnormal red blood cells that affect oxygen delivery.
- Early diagnosis through newborn screening and blood tests is vital.
- Communities need empowerment to advocate for better healthcare access and support.
- Knowing your sickle cell trait status helps in family planning and prevention strategies.

๐—›๐—ผ๐˜„ ๐—ฌ๐—ผ๐˜‚ ๐—–๐—ฎ๐—ป ๐—›๐—ฒ๐—น๐—ฝ:
- Get tested or encourage others to get screened, especially before pregnancy.
- Support local and global awareness campaigns.
- Share accurate information about SCD symptoms, treatment, and prevention.
- Advocate for better healthcare policies and resources for affected communities.

Letโ€™s unite on 19 June 2025 to empower communities and create lasting change for people living with sickle cell disease.

#WorldSickleCellDay #SickleCellAwareness #SickleCellDisease #GlobalActionLocalImpact #EmpowerCommunities #GetTested #HealthEquity #GeneticDisorders #EarlyDiagnosis #SupportSickleCellPatients #HealthForAll #BloodDisorders #KnowYourStatus #SCABPharmacy

Africa: Sickle Cell Disease Remains a Challenge in Africa!: [The Point] Sickle cell disease refers to a group of inherited blood disorders with symptoms like anaemia and blocked blood vessels. About 80% of the world's sickle cell disease cases occur in sub-Saharan Africa. Lack of access to comprehensive healthcare in the region adds to the burden of the disease. http://newsfeed.facilit8.network/TLPdqV #SickleCellAwareness #HealthcareForAll #AfricaHealth #SickleCellDisease #HealthEquity
Beam Therapeutics reveals breakthrough sickle cell treatment data at EHA2025, showcasing innovative base editing technology for potential long-term genetic therapy solutions. #Biotech #SickleCellDisease

โ€˜Groundbreakingโ€™ sickle cell disease treatment approved for NHS use in England
Clinical trials find one-time gene therapy exa-cel offers โ€˜functional cureโ€™ in 96.6% of patients

https://www.theguardian.com/society/2025/jan/31/groundbreaking-potential-cure-for-sickle-cell-in-england-approved-for-nhs-use

#142holdheap #SickleCellDisease #GeneTherapy #Medicine

โ€˜Groundbreakingโ€™ sickle cell disease treatment approved for NHS use in England

Clinical trials find one-time gene therapy exa-cel offers โ€˜functional cureโ€™ in 96.6% of patients

The Guardian
โ€˜Groundbreakingโ€™ sickle cell disease treatment approved for NHS use in England

Clinical trials find one-time gene therapy exa-cel offers โ€˜functional cureโ€™ in 96.6% of patients

The Guardian

Sickle cell retinopathy

In sickle cell disease, widefield fluorescein angiography (FA) is superior for evaluating peripheral ischemia. This imaging modality captures extensive retinal areas, enabling the detection of non-perfusion zones, neovascularization, and other ischemic changes often missed in standard FA. Widefield FA is critical for guiding management strategies, including laser photocoagulation. #SickleCellDisease #WidefieldFA #PeripheralIschemiaโ€ฆ

https://retinography.org/sickle-cell-retinopathy-4/

Sickle cell retinopathy

In sickle cell disease, widefield fluorescein angiography (FA) is superior for evaluating peripheral ischemia. This imaging modality captures extensive retinal areas, enabling the detection of nonโ€ฆ

"It was at Barnes that sheโ€™d learned people with sickle cell could have children after all. As she started coming here, sheโ€™d seen other patients with kids in tow. She hadnโ€™t thought that was possible."

For STAT, Eric Boodman follows a #SickleCellDisease patient as she juggles pain, doubt, and the challenges of a complex disease: https://www.statnews.com/2024/11/11/coercive-care-series-sickle-cell-pregnancy-risks-unwanted-sterilizations

#Longreads #Health #Medicine #Sterilization

'What's your pain right now?' Sickle cell, loss, and survival in America

For a St. Louis woman wrestling with pain and a coercive sterilization, crises come in waves

STAT