Solving a marine mystery: How #anemonefish avoid stings from their sea anemone hosts
https://phys.org/news/2025-02-marine-mystery-anemonefish-sea-anemone.html

Anemonefish use #SialicAcid metabolism as Trojan horse to avoid giant #SeaAnemone stinging: Natacha Roux et al. https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02144-8

"anemonefish have evolved to maintain very low levels of sialic acid in their skin mucus to avoid triggering the release of stinging cells in their sea anemone hosts."

Solving a marine mystery: How anemonefish avoid stings from their sea anemone hosts

The clownfish-anemone living arrangement is one of the most widely recognized examples of symbiosis. Researchers have made a breakthrough in understanding how anemonefish can live safely among sea anemones without being stung by their venomous tentacles, solving a century-long mystery.

Phys.org

In this month's interesting facts we take a look at CMP-Sialic acid, a sugar donor which is key in the #sialylation of #glycans; and its synthetase.

Read more: https://research.bidmc.org/ncfg/blog/facts-about-cmp-sialic-acid-nature

For more interesting facts: https://research.bidmc.org/ncfg/interestingfacts/interesting-facts-about-glycans

#glycotime #sialicacid

National Center for Functional Glycomics (NCFG)

A Sugar Connection: How the Original SARS-CoV-2 Strain May Have Jumped to Humans
Scientists discovered that the original SARS-CoV-2 strain could bind to sugars called sialic acids on human cells, a trait not retained by later strains such as Delta and Omicron.
https://scitechdaily.com/a-sugar-connection-how-the-original-sars-cov-2-strain-may-have-jumped-to-humans/ #COVIDー19 #strain #SialicAcid #virus
A Sugar Connection: How the Original SARS-CoV-2 Strain May Have Jumped to Humans

The original SARS-CoV-2 strain was found to bind to sialic acids (a class of sugars) on human cells, a trait not seen in later strains. This discovery, made by the Rosalind Franklin Institute and University of Oxford, offers insights into the virus's transmission and evolution, correlates with previ

SciTechDaily

Hi #mastodon

Suppose It's high time for my #introduction πŸ‘‹ I'm a 4th year grad student working with Jim Paulson @ Scripps Research where I develop therapies targeting the #SialicAcid immune axis to combat #cancer & viral infection.

Besides #glycans & #glycotime (obvi.) recent interests include #ProteinEngineering, #Phage Display, #DELs, #TPD, #Bioorthogonal Chemistry and #ChemBio at large.

Intrigued by the #startup life & low-key shopping around for #postdoc ops

#mastodonmigration 🐘

Hi All, I am a fourth-year PhD candidate in Prof. Lara Mahal Lab @glycocode. Working on #GeneExpression regulation by #miRNAs, #sialicacid, So excited to be here and have scientific discussion!