CellBioNewsMar 8, 2024

#CRISPRlnc: New #lncRNA-specific #SgRNA design method proposed.

https://phys.org/news/2024-03-crisprlnc-lncrna-specific-sgrna-method.html

CRISPRlnc: New lncRNA-specific SgRNA design method proposed

Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts. Currently, CRISPR/Cas9 is a promising RNA-guided genome editing technology consisting of a Cas9 nuclease and a single-guide RNA (sgRNA). Considering the significant differences between lncRNAs and protein-coding genes, it is necessary to investigate sgRNA design method optimized for lncRNAs.

Phys.org
CellBioNewsDec 22, 2023

#CRISPR/Cas9's role in fine-tuning #miRNA expression in #tetraploid #potatoes.

#agriculture #sgRNA #MIR160

https://phys.org/news/2023-12-crisprcas9-role-fine-tuning-mirna-tetraploid.html

CRISPR/Cas9's role in fine-tuning miRNA expression in tetraploid potatoes

MicroRNAs (miRNAs) play a crucial role in plant gene regulation, with their biogenesis involving complex processes. Fine-tuning miRNAs is a powerful biotechnology strategy that can improve plant performance in the field, such as adjusting crop tolerance to abiotic or biotic stress.

Phys.org
JIPBApr 18, 2023
Everything's coming up🌹🌹🌹
Check out our latest #JIPB cover, featuring Wang et al. and their powerful toolbox for functional #genomics and #molecular #breeding in #roses.
https://jipb.net/EN/10.1111/jipb.13421
@wileyplantsci
#JIPB #PlantScience #CRISPR #sgRNA #Agrobacterium #callus