Alex SilverAs I don't have much history here yet, here's a bit of a summary. Over the past few years on the bird site (@AlexSilverMSTP), I've tried to amplify #science and #medicine news from colleagues (#DoubleDocs and #SciMed) and followers. I also intermittently post original #research and review manuscripts that I've worked on, such as this review we did on #germline #genetic risk for #ClonalHematopoiesis: https://www.nature.com/articles/s41576-021-00356-6
Germline risk of clonal haematopoiesis - Nature Reviews Genetics
Silver, Bick and Savona discuss our latest understanding of clonal haematopoiesis (CH), which is an expansion of blood cell populations with shared somatic mutations. They focus on human germline risk variants and on how these are linked to different forms of CH and their associated disease pathologies.