Archival copy posted on #Zenodo (same paper as on #SSRN “Climate Change and Mental Health: The Hidden Impact of Temperature Fluctuations.”

🔗 https://zenodo.org/records/19414712
#Schizophrenia #MentalHealth

Climate Change and Mental Health: The Hidden Impact of Temperature Fluctuations

Climate change discussions predominantly focus on ecological and economic consequences,frequently neglecting profound psychological implications. This paper examines the criticallink between temperature fluctuations and mental health stability, particularly for vulnerablepopulations with pre-existing conditions such as schizophrenia. By integrating physiologicalmechanisms—including regulatory disruption and the impairment of circadian rhythms—with personal observation and selected case contexts, this note highlights a “cascade ofvulnerability”. Special attention is given to lessons from disaster-recovery regions such asFukushima, arguing that environmental stability must be recognised as a medical necessity.The paper concludes that proactive mental health infrastructure and climate adaptationstrategies are essential for a resilient and equitable society. This paper is non-clinical andnon-diagnostic, and it does not propose diagnostic criteria or treatment protocols.

Zenodo

I'm convinced #Trump suffers from #schizophrenia

And it may be his only defense

Bible Gateway passage: Matthew 17:14-18 - New International Version

Jesus Heals a Demon-Possessed Boy - When they came to the crowd, a man approached Jesus and knelt before him. “Lord, have mercy on my son,” he said. “He has seizures and is suffering greatly. He often falls into the fire or into the water. I brought him to your disciples, but they could not heal him.” “You unbelieving and perverse generation,” Jesus replied, “how long shall I stay with you? How long shall I put up with you? Bring the boy here to me.” Jesus rebuked the demon, and it came out of the boy, and he was healed at that moment.

Bible Gateway
創意與精神疾病的關聯:藝術家都有精神分裂嗎? | TechOrange 科技報橘

想到藝術家,你會想到什麼?瘋瘋癲癲、思考方式與常人不同?或是內心充滿小劇場,無法好好管理自己的情緒、甚至有分裂人格?常說藝術是痛苦之下的產物,但是藝術家真的都是瘋子與神經病嗎?心理學家兼神經學家 Nancy Andreasen 的這本書The Creating Brain: The Neuroscience of

TechOrange 科技報橘

This brief highlights how genetic factors can influence cognitive flexibility and reality-updating processes, areas frequently examined by mental health professionals in relation to psychosis and decision-making. The finding emphasizing thalamus–prefrontal cortex circuitry offers a concise example of neural pathways that may underlie adaptive versus perseverative thinking, a pattern clinicians encounter when working with schizophrenia and related conditions.

Article Title: A gene mutation may trap the brain in the wrong reality in schizophrenia patients

Link to Science Daily Mind-Brain News: https://www dot sciencedaily dot com/releases/2026/04/260402042740 dot htm

A gene mutation may trap the brain in the wrong reality in schizophrenia patients
https://www dot sciencedaily dot com/releases/2026/04/260402042740 dot htm
A newly identified gene mutation may help explain why schizophrenia patients struggle to update their understanding of reality. The mutation disrupts a brain circuit involved in flexible decision-making, causing mice to stick with outdated choices even when conditions change. Researchers pinpointed the issue to a key thalamus–prefrontal cortex pathway. By reactivating this circuit, they were able to restore normal behavior—raising hope for future therapies.
via Mind & Brain News -- ScienceDaily https://www dot sciencedaily dot com/news/mind_brain/
April 3, 2026 at 03:10AM

#genetics
#schizophrenia
#neurocircuitry
#thalamusprefrontal
#cognitiveflexibility

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Ketamine for negative and depressive symptoms in schizophrenia: the evidence so far (Diendorfer, et al, 2026 https://pubmed.ncbi.nlm.nih.gov/41918583/ #ketamine #psychedelics #depression #schizophrenia #ketaminetherapy #mentalhealth
I dropped out of school yesterday. I simply couldn't see myself in a world that didn't have room for me. It hurts so much because I really wanted it. But I don't want to compromise who I am to fit into a box I can't fit into ❤️‍🩹 So now I'm on my way to the job center to apply for social assistance 😔 I have a good plan for what I want and it will definitely be much better than being a health administrative coordinator, but it still hurts that my dream couldn't come true 🩷

#mentalhealth #schizophrenia #adhd #cptsd #trauma #depression #ootd #anxiety #recovery #psychology #mentor #recoverymentor #redhair #fashion #fashionphotography

@MaFu55 @dzne They find that increased C4 reduces #synapse density while decreasing #microglial contact with synapses. This challenges the simple "more pruning" view and points to disrupted microglial surveillance and signaling instead. Together, this links C4–CR3 signaling to circuit-level dysfunction, providing a mechanistic bridge between immune genetics and synaptic pathology in #schizophrenia.

Huge congratulations to Nala & Naya and all co-authors on this excellent work! 🎉

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

did some art like a did many years ago #myart #abstract #schizophrenia #schizospec #art