In early synaptogenesis, localised microtubule severing facilitates axonal pre-patterning 🧠

Matthew Davies (#Rumpf_lab) highlights a beautiful #preprint from the #ErikaHolzbaur lab.

“This preprint…enhances our capacity to study early stages of presynaptic patterning”

#preLight 👉 https://prelights.biologists.com/highlights/spastin-locally-amplifies-microtubule-dynamics-to-pattern-the-axon-for-presynaptic-cargo-delivery-v2/

#neuroscience #synaptogenesis #synapses #axons #microtubules #patterning #development