https://www.nature.com/articles/s41591-024-02978-9
A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma - Nature Medicine
Multiomics and spatial mapping of tumor samples derived from a real-world cohort of patients with advanced renal cell carcinoma, as well as integration of transcriptomics and human leukocyte antigen genotyping data, provides a machine learning-derived signature of response to immune checkpoint blockade.




