Ultrastructure expansion microscopy reveals nanoscale organization of tubulin PTMs in mammalian photoreceptors, and the role of glutamylation balance for ciliary architecture
#RefereedPreprint c/o @ReviewCommons by Virginie Hamel, Paul Guichard @Centriolelab, Carsten Janke et al
https://www.embopress.org/doi/full/10.1038/s44318-024-00284-1
Cross-species analysis in Oryzias fish, measuring the timing of embryonic body axis segmentation and overall organismal size, suggests that timing and size control are dissociable modules
Alexander Aulehla, Ewan Birney @ewanbirney et al
#RefereedPreprint c/o @ReviewCommons
https://www.embopress.org/doi/full/10.1038/s44318-024-00186-2

Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics

#RefereedPreprint c/o @ReviewCommons by Véronique Le Cabec, Sébastien Carréno, Renaud Poincloux and colleagues shows that #macrophages do not require the ERM family proteins for phagocytosis and cell migration, suggesting divergence of macrophage cortical properties

https://www.embopress.org/doi/full/10.1038/s44318-024-00173-7

New #RefereedPreprint c/o @ReviewCommons:
John O’Neill, Andrew Beale and colleauges show that protein homeostasis is maintained by circadian rhythms in protein synthesis and degradation rates, leading to daily proteome renewal
https://www.embopress.org/doi/full/10.1038/s44318-024-00121-5
Apicomplexan parasites do have G2 cell cycle phases – as long as they undergo binary division like Toxoplasma gondii!
Lauren Hawkins, Elena Suvorova et al find its control by CDK/cyclin pair Crk4-Cyc4 and a Cdt1-related inhibitor of reduplication
#RefereedPreprint c/o @ReviewCommons
https://www.embopress.org/doi/full/10.1038/s44318-024-00095-4
TLDc-domain proteins Rtc5 and Oxr1 regulate assembly and subcellular localization of the yeast V-ATPase
Ayelén González Montoro and coworkers
#RefereedPreprint c/o @ReviewCommons
https://www.embopress.org/doi/full/10.1038/s44318-024-00097-2

What’s the role of RNAi for antiviral immunity?
Human Dicer lacking its self-restraining helicase domain can in fact activate antiviral and inflammatory responses independent of RNAi

#RefereedPreprint c/o @ReviewCommons by Sébastien Pfeffer and colleagues

https://www.embopress.org/doi/full/10.1038/s44318-024-00035-2

#Centrosome growth in Drosophila embryos is connected to nuclear division cycles and regulated by the cell-cycle oscillator, rather than by a limiting component as in worms

#RefereedPreprint c/o @ReviewCommons by Jordan Raff and coworkers

https://www.embopress.org/doi/full/10.1038/s44318-023-00022-z

Next #RefereedPreprint c/o @ReviewCommons published in @embojournal
Gönczy et al @epfl_en show that #centriole elimination during C. #elegans #oogenesis occurs in two steps, initiated by loss of central tube protein SAS-1
https://www.embopress.org/doi/full/10.15252/embj.2023115076

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630