SciTech Chronicles. . . . . . . . .Feb 14th, 2025

When you ask for clarity, be ready for disappointment Vol II No 40 343 links Curated The recycled solar cell has the same efficiency as the ...

Toward video generative models of the molecular world

As the capabilities of generative AI models have grown, you've probably seen how they can transform simple text prompts into hyperrealistic images and even extended video clips.

Phys.org
I would appreciate any advice on analyzing a protein structure using #AlphaFold, Colab, or #RFDiffusion models to identify new interactors. If anyone is interested, I would love to connect via Teams and collaborate. 🧬🖥️ #deeplearning

Nature News covers the antibody design preprint.

I'll mischievously suggest that this is what Nature as a bioRxiv overlay journal could look like.

https://www.nature.com/articles/d41586-024-00846-7
#RFdiffusion #proteinDesign #cellBiology

‘A landmark moment’: scientists use AI to design antibodies from scratch

Modified protein-design tool could make it easier to tackle challenging drug targets — but AI antibodies are still a long way from reaching the clinic.

Wow, this looks exciting!

“Atomically accurate de novo design of single-domain antibodies”

from the Baker lab (of course)

https://www.biorxiv.org/content/10.1101/2024.03.14.585103v1

#RFdiffusion #proteinDesign #cellBiology

AI generates proteins with exceptional binding strengths

A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University of Washington School of Medicine used software to create protein molecules that bind with exceptionally high affinity and specificity to a variety of challenging biomarkers, including human hormones.

Phys.org
AI tools are designing entirely new proteins that could transform medicine

Digital art techniques can now devise custom, working biomolecules on demand.