From a clinical standpoint, the study suggests that the association between planned cesarean delivery and offspring mental health risk may reflect shared genetic liability rather than a direct causal effect of birth mode. The research links higher polygenic risk scores for schizophrenia, bipolar disorder, and depression to planned cesarean births, while findings for acute cesareans differ, pointing to familial confounding. This nuance is relevant to psychiatrists, clinical social workers, therapists, and other mental health professionals who interpret observational data or discuss birth-related risk with families, highlighting the importance of genetic context in risk interpretation.

Article Title: Genetic factors likely confound the link between c-sections and offspring mental health

Link to PsyPost Article: ift dot tt/O5PW86p

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#Genetics #MentalHealth #CesareanSection #PolygenicRisk #PsychiatryResearch

SARS-CoV-2 infection and COVID-19 outcomes across mental disorders and the role of sex: A register-based study from Catalonia

https://www.sciencedirect.com/science/article/pii/S0165178124006103

Highlights
• We found varying risks of infection and severe COVID-19 across mental disorders.
• All mental disorders except stress-related ones showed increased COVID-19 mortality.
• Women with depressive and neurotic disorders were especially vulnerable to COVID-19.

#PsychiatricDisorders #SevereCOVID19 #ElectronicHealthRecords #EHR #PADRIS #gender #mortality #COVID19 #Psychiatry #PsychiatryResearch #Catalonia #Catalunya #IRSJD #PSSJD #CIBERSAM