Spannende #Psilocybin-Studie, die theoretisch nachgewiesen hat, dass das #Psilocin nicht einmal der stärkste Wirkstoff im Mix der Pilze sein könnte; außerdem ist ein MAO-Hemmer dabei:

https://www.psypost.org/psilocybin-might-not-be-the-most-psychoactive-ingredient-in-magic-mushrooms-new-research-suggests/

Psilocybin might not be the most psychoactive ingredient in magic mushrooms, new research suggests

Published in Scientific Reports, new research provides evidence that minor compounds in psychedelic mushrooms work alongside psilocybin to interact with brain receptors. This chemical teamwork explains why whole mushroom extracts often affect people differently than isolated, lab-made psilocybin.

PsyPost Psychology News

I want to be clear about where I stand. I support classic psychedelics like psilocybin, psilocin, Mescaline, LSD, and also cannabis, not because I think everyone should use them, but because I believe in the freedom of consciousness.

This isn’t a war on drugs; it’s a war on consciousness itself. The stigma surrounding psychedelics has been built and reinforced by decades of fear-based media and institutional control. Simply talking about these substances bout to send some people on the Fediverse into outrage, which says more about the conditioning than about the substances themself.

I am proudly pro-psychedelics. For those struggling with depression, PTSD, or deep emotional wounds, these tools, when used with respect and proper guidance, can offer genuine healing. They can also serve as a way for anyone seeking to explore the layers of their own ego and understand themselves on a deeper level.

But as we know, society and cultures often treat altered states of mind as something dangerous, when in reality, they are among humanity’s oldest pathways to growth, connection, and awakening.

If you want to explore consciousness the way I do, you can visit https://doubleblindmag.com for insightful stories and perspectives on psychedelics, healing, and self-discovery.

You can also experience their insights in video form on their YouTube channel at https://www.youtube.com/@DoubleBlind/videos.

#Psychedelics #Psychedelic #Psychedelia #LSD #Psilocybin #Psilocin #Mescaline #DMT #Ayahuasca #MDMA #2CB #Weed #Cannabis #Drugs

DoubleBlind Magazine

Untold stories about the expansion of psychedelics around the globe

DoubleBlind Mag

As we move into 2026, I want to be clear about where I stand. I support classic psychedelics like psilocybin, psilocin, Mescaline, LSD, and also cannabis, not because I think everyone should use them, but because I believe in the freedom of consciousness.

This isn’t a war on drugs; it’s a war on consciousness itself. The stigma surrounding psychedelics has been built and reinforced by decades of fear-based media and institutional control. Simply talking about these substances bout to send some people on the Fediverse into outrage, which says more about the conditioning than about the substances themself.

I am proudly pro-psychedelics. For those struggling with depression, PTSD, or deep emotional wounds, these tools, when used with respect and proper guidance, can offer genuine healing. They can also serve as a way for anyone seeking to explore the layers of their own ego and understand themselves on a deeper level.

But as we know, society and cultures often treat altered states of mind as something dangerous, when in reality, they are among humanity’s oldest pathways to growth, connection, and awakening.

For reference, I celebrate Bicycle Day every year (4/19), and you can learn more about its history and meaning here: https://www.youtube.com/watch?v=InD5_Ml1OxQ

#Psychedelics #Psychedelic #Psychedelia #LSD #Psilocybin #Psilocin #Weed #Canabis #Drugs

Acid's Annual Holiday: Bicycle Day 🚲🌈 | DoubleBlind

YouTube

A groundbreaking 2025 study has revealed that psilocin, the active compound in psychedelic mushrooms, can extend the lifespan of human skin and lung cells by more than 50 percent. This discovery highlights an unexpected role for psychedelics beyond their well-known effects on the brain, pointing to potential applications in cellular health and longevity.

Researchers found that psilocin influences cellular pathways related to stress resistance and repair mechanisms. By enhancing the cells’ ability to withstand damage and maintain function, psilocin effectively slows down cellular aging. This could have far-reaching implications for regenerative medicine, anti-aging research, and treatments for age-related diseases.

While the study was conducted at the cellular level and not yet tested in whole organisms, the results are promising. They suggest that compounds traditionally associated with mental health and consciousness studies may also hold keys to improving physical health and lifespan at the cellular level.

The findings also raise exciting questions about the broader impact of psychedelics on human biology. Could psilocin or related compounds one day become tools to support tissue regeneration, healthy aging, or even organ preservation? Scientists are now exploring these possibilities while investigating safety, dosage, and mechanisms of action.
This research underscores the incredible potential of compounds found in nature and reminds us that even substances with a long history of cultural and spiritual use can reveal new benefits under scientific scrutiny.

Core discovery & science
#MedicalBreakthrough #CellularLongevity #LifeSciences #RegenerativeMedicine #AntiAgingResearch

Compound & psychedelics
#Psilocin #PsychedelicScience #NaturalCompounds #PlantMedicine #BioInnovation

Impact & future applications
#HealthyAging #FutureOfMedicine #InnovativeMedicine #CuttingEdgeScience #LongevityResearch

Loughor man jailed for running multi‑drug supply operation

Oliver Nancarrow, of Beili Glas, was sentenced at Swansea Crown Court to three years and nine months in prison after pleading guilty to possession and being concerned in the supply of cocaine, ecstasy, psilocin, ketamine, cannabis, LSD and MDMA, as well as possessing criminal property.

The court heard Nancarrow came to police attention during an unrelated investigation when officers identified his number in seized phones. Subsequent enquiries linked him to a drugs line offering a range of substances, with bulk text messages advertising prices and even “tester” samples of cocaine to potential customers.

When South Wales Police’s organised crime team searched his home on 7 July, they found quantities of Class A and B drugs, £3,410 in cash, and six mobile phones — two of which contained messages tying him to the supply of a large list of drugs. Officers also recovered packaging branded “Head Chef”, hidden storage containers, and lists of debts.

In total, police seized cocaine, ecstasy tablets and powder, LSD tabs, magic mushrooms, cannabis and ketamine, with an estimated street value of more than £13,000.

Judge Geraint Walters described the operation as “sophisticated”, noting concealment methods including magnetic storage boxes designed to attach to vehicles.

Sergeant Luke Tucker, of South Wales Police, said:

“Oliver Nancarrow is another young man who has now thrown away years of his life due to involving himself in the illegal drugs trade. Like so many others before him, he was motivated only by financial greed, and did not care for how many lives would be damaged as a result of the drugs being used. He is rightfully starting a sizeable sentence in prison.”

Nancarrow will serve up to half his sentence in custody before being released on licence.

#Cannabis #cocaine #Crime #drugs #Ecstasy #ketamine #Loughor #LSD #MDMA #psilocin #SouthWalesPolice

@erictopol Show of hands: Who here hasn't ever wished for "improved fur quality"?

🙋️🙋️🙋️

But wait, there's more!

「Summary: Psilocybin, the active compound derived from psychedelic mushrooms, significantly delayed cellular aging and extended lifespan in a preclinical study. Researchers observed a 50% increase in the lifespan of human skin and lung cells and a 30% increase in survival in aged mice treated with psilocybin.

The compound appeared to reduce oxidative stress, preserve telomeres, and improve DNA repair, all key to slowing aging. These findings suggest psilocybin may one day enhance not just lifespan but also quality of life in aging populations.」

Good news:
🔹TBD

Dire news:
🔻️All septuagenarian and older autocrats and despots will hang onto power for years if not decades longer.
🔻️This natural mushroom compound will be banned and Big Pharma will create artificial analogues that the general public can never afford.
🔻️See above: War on Magic Mushrooms...
🔻️Countless mice will have longer life with more luscious coat but still in the same miserable cage...

https://neurosciencenews.com/psilocybin-longevity-aging-29425/

#antiaging #psilocin #psilocybin #magicmushrooms #shrooms

Psilocybin Shows Promise as Anti-Aging Therapy - Neuroscience News

Neuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

Neuroscience News
BookWyrm

Social Reading and Reviewing

Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity.

This ‘fundamental’ study into the effects of #psilocin on human neurons: https://elifesciences.org/reviewed-preprints/104006?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

If medicine compounds like #mdma #ketamine #lsd #psilocybin #psilocin #dmt where rescheduled, these off-patent compounds could be manufactured at scale and FDA-approval of LYKOS/MAPS New Drug Application for a patented form of #mdma wouldn't matter as much. Research outside of LYKOS supports the use of these medicine compounds for a number of mental health indications especially when supported by licensed mental health providers in psychotherapy. #legalizepsychedelicmedicines #fda #psychedelics