Proteins still hold secrets. New bonds discovered reveal hidden complexities, opening doors to medical and scientific breakthroughs. #ProteinChemistry #ScientificDiscovery #Biotechnology

https://geekoo.news/uncovering-hidden-chemistry-in-proteins/

Uncovering Hidden Chemistry in Proteins | Geekoo

Scientists at the University of Göttingen have discovered previously undetected chemical bonds in proteins, revealing a new layer of complexity in protein chemistry. This breakthrough has significant implications for understanding how proteins respond to oxidative stress and could inform future advancements in drug design and synthetic biology.

Geekoo

TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis
https://www.nature.com/articles/s41556-021-00641-w

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Understudied protein blobs have global effects on cell biochemistry
https://phys.org/news/2024-09-understudied-protein-blobs-global-effects.html
https://news.ycombinator.com/item?id=41602473

Biomolecular condensates regulate cellular electrochemical equilibria
https://www.cell.com/cell/abstract/S0092-8674(24)00909-7

#biology #biochemistry #electrochemistry #ProteinChemistry #BiomolecularCondensates #MolecularBiology #PhaseSeparation #PhaseLocalization #ProteinBlobs

TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis - Nature Cell Biology

Esposito et al. show that TGF-β-induced DACT1 forms biomolecular condensates that sequester CK2 to repress Wnt signalling and modulate bone metastasis in cancer.

Nature

A Newfound Source of Cellular Order in the Chemistry of Life
Inside cells, droplets of biomolecules called condensates merge, divide and dissolve
Their dance may regulate vital processes
https://www.quantamagazine.org/a-newfound-source-of-cellular-order-in-the-chemistry-of-life-20210107

#biology #biochemistry #ProteinChemistry #BiomolecularCondensates #MolecularBiology #PhaseSeparation #PhaseLocalization #ProteinDroplets

A Newfound Source of Cellular Order in the Chemistry of Life

Inside cells, droplets of biomolecules called condensates merge, divide and dissolve. Their dance may regulate vital processes.

Quanta Magazine

[thread] Biomolecular condensates
https://en.wikipedia.org/wiki/Biomolecular_condensate

* biochemistry - biomolecular condensate: membrane-less subcellular domains
* specialized cellular functions
* composition not controlled by bounding membrane
* form/maintain organization by var. processes
* phase separation of proteins, RNA, biopolymers into colloidal emulsions, gels, liquid crystals, solid crystals, aggregates

#biochemistry #ProteinChemistry #BiomolecularCondensates #PhaseSeparation #PhaseLocalization #ProteinDroplets

Biomolecular condensate - Wikipedia

Biochemist with a focus on protein folding and really wish my hardware could run alphafold. Wide range of interests with never enough time to cover everything.

#Introduction
#science #immunology #virology #queer #parenting #SpecialNeeds #linux #OpenSuse #FOSS #FrameworkLaptop #biochemistry #ProteinChemistry #phage #CellBiology #MedicinalChemistry