https://link.springer.com/protocol/10.1007/978-1-0716-4502-4_11
#ChemBio #Chemistry #Bacteria #Proteases #Probes
Profiling endogenous #airway #proteases and antiproteases and measuring proteolytic #activation of #Influenza #HA using in vitro and ex vivo human airway surface #liquid samples, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.06.14.599031v1?rss=1
This #assay presents a direct and efficient method of evaluating the proteolytic environment of human airway samples in assessment of therapeutic treatment, exposure, or underlying disease.
Getting #protein factories to run—How #deubiquitinating #enzymes moonlight as #Fubi #proteases.
https://phys.org/news/2023-08-protein-factories-runhow-deubiquitinating-enzymes.html
The small protein ubiquitin is particularly famous for marking proteins for degradation but it has also been shown to regulate virtually all cellular processes. In parallel to the ubiquitin system various other ubiquitin-like modifiers have evolved, of which Fubi is particularly poorly studied despite its immunomodulatory activity.
A quick #Introduction
Hello there, Mastodon World!
I am a Ramon y Cajal Research Investigator and Junior Group Leader at the IBMB-CSIC in Barcelona. We apply our expertise in #StructuralBiochemistry and #ProteolyticFlagellins to #SyntheticMicrobiology, and aim to functionalize bacterial #Flagella for biotechnology and biomedicine.
#Science #Proteins #Proteases #Microbiology #SyntheticBiology