I am very happy that Michaela Prothiwa joined us today for a department visit and a lecture. She gave a very interesting lecture on "Chemical strategies to understand bacterial immune evasion".
https://link.springer.com/protocol/10.1007/978-1-0716-4502-4_11
#ChemBio #Chemistry #Bacteria #Proteases #Probes
I am very happy that @[email protected] joined us today for a department visit and a lecture. She gave a very interesting lecture on "Chemical strategies to understand bacterial immune evasion". link.springer.com/protocol/10.... #ChemBio #ChemSky #Bacteria #Proteases #Probes

Profiling endogenous #airway #proteases and antiproteases and measuring proteolytic #activation of #Influenza #HA using in vitro and ex vivo human airway surface #liquid samples, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.06.14.599031v1?rss=1

This #assay presents a direct and efficient method of evaluating the proteolytic environment of human airway samples in assessment of therapeutic treatment, exposure, or underlying disease.

Getting protein factories to run—How deubiquitinating enzymes moonlight as Fubi proteases

The small protein ubiquitin is particularly famous for marking proteins for degradation but it has also been shown to regulate virtually all cellular processes. In parallel to the ubiquitin system various other ubiquitin-like modifiers have evolved, of which Fubi is particularly poorly studied despite its immunomodulatory activity.

Phys.org
Hmm, interesting questions: when doing in-vitro protease digests with recombinant protease, do I exclude self-cleavages of the protease from the putative cleavages as it might be rather an artefact of the excess protease addition? #Proteases #Ntermini

A quick #Introduction

Hello there, Mastodon World!
I am a Ramon y Cajal Research Investigator and Junior Group Leader at the IBMB-CSIC in Barcelona. We apply our expertise in #StructuralBiochemistry and #ProteolyticFlagellins to #SyntheticMicrobiology, and aim to functionalize bacterial #Flagella for biotechnology and biomedicine.

#Science #Proteins #Proteases #Microbiology #SyntheticBiology