Søren GrubbAt the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)
Results: In this study of the #MICrONS 🐭👁️-cortex 3D #ElectronMicroscopy dataset, I show how the shape of #Contractile #MuralCells transition from #PenetratingArteriole to #PrecapillarySphincter to #Capillaries. Vascular lumen = blue, mural cells = various colors (5/15)
The function 🧑🔧 of the #PrecapillarySphincter is to control the #BloodFlow to the #Capillaries, securing adequate distribution of blood flow between the upper and lower cortical layers. For more, check these🧵: https://bit.ly/3hUEytP and https://tinyurl.com/4e2w3x9n (4/15)
Søren Grubb @[email protected] on Twitter
“Today our #neuroscience #research #paper about #PrecapillarySphincters in the #Brain is live on @NatureComms: https://t.co/dIQb5Cr3BG. I’m so proud of our work @Uni_Copenhagen @UCPH_Health @Neuroscience_dk and would like to share it with you in the following tweets. #happy (1/10)”