Dustin Miller PolyInnovatorJan 30, 2025
One of the guests on the #polycast brought to my attention that #multipotentialites are in the biological term: #Pluripotent Able to adapt to any new environment. Which I thought was genius way of explaining it. After adapting they get formed into that new cell, and become more of a generalist over time.
preLightsJan 31, 2024

The search for i-cells: Andreas Denner and team #TechnauLab characterise a putative stem cell population in the sea anemone Nematostella vectensis.

preLight by Isabella Cisneros which includes an author response! 👀

#preLight 👉 https://prelights.biologists.com/highlights/nanos2-cells-give-rise-to-germline-and-somatic-lineages-in-the-sea-anemone-nematostella-vectensis/

#cnidarian #StemCells #multipotent #nematostella #pluripotent #DevBio #CellBiology

Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis - preLights

The search for i-cells: @TechnauLab characterizes a putative stem cell population in the sea anemone Nematostella vectensis

preLights
CellBioNewsDec 26, 2023

A chemically defined, #xeno_free culture system for #culturing and deriving #monkey #pluripotent stem cells in vitro.

#bioengineering #signalling #luciferase #chimera

https://phys.org/news/2023-12-chemically-xeno-free-culture-culturing-deriving.html

A chemically defined, xeno-free culture system for culturing and deriving monkey pluripotent stem cells in vitro

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models. These similarities manifest at the genetic, physiological, socio-behavioral, and central nervous system levels, making NHPs uniquely suitable for research into stem cell therapy and increasingly used in preclinical trials to test the safety and efficacy of biotechnology therapies.

Phys.org
Victoria Stuart 🇨🇦 🏳️‍⚧️Aug 28, 2023

Scientists wipe cell memory to reprogram as a stem cell
https://www.uwa.edu.au/news/Article/2023/August/Scientists-find-way-to-wipe-a-cells-memory-to-reprogram-it-as-a-stem-cell
https://news.ycombinator.com/item?id=37286860

Transient naive reprogramming corrects hiPS cells functionally & epigenetically
https://www.nature.com/articles/s41586-023-06424-7

* epigenome reconfiguration wh. cells reprogrammed to human induced pluripotent stem cells
* epigenomes of hiPS cells, hES differ significantly; affects hiPS cell function
* transient-naive-treatment reprogramming emulates embryonic epigenetic reset

#StemCells #pluripotent #epigenetics

Scientists find way to wipe a cell's memory to reprogram it as a stem cell

In a groundbreaking study published today in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine.

CellBioNewsJul 8, 2023

Study uncovers the secrets of #plant #regeneration.

#HOMEOBOX #WOX13 #pluripotent

https://phys.org/news/2023-07-uncovers-secrets-regeneration.html

Study uncovers the secrets of plant regeneration

Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction. This process involves the de novo (or new) formation of a shoot apical meristem (SAM) that gives rise to lateral organs, which are key for the plant's reconstruction.

Phys.org
Investigate Explore DiscoverJul 7, 2023

Unleashing the Power of Totipotent Cells: Decoding Developmental Potential
Learn about the different molecular processes underlying skin wound healing

This is a summary of the paper: Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

By: Yang et al.

#shorts #science #pluripotent #totipotent #cellbiology

The EMBO JournalMar 17, 2023
Induction of fetal meiotic oocytes from embryonic stem cells in cynomolgus monkeys
Mitinori Saitou and coworkers establish in vitro maturation of monkey #pluripotent #stemcells into fetal #oocytes as a unique new model for human #oogenesis
https://www.embopress.org/doi/10.15252/embj.2022112962
Road Not TakenJan 21, 2023

Fascinating. Good #science #research #biology #cells #embryos #embryology #pluripotent #StemCells

https://scitechdaily.com/a-biological-wonder-harvard-researchers-discover-embryonic-origins-of-adult-pluripotent-stem-cells/

A Biological Wonder: Harvard Researchers Discover Embryonic Origins of Adult Pluripotent Stem Cells

Stem cells are a remarkable biological wonder that have the ability to repair, replace and regenerate cells. In most animals and humans, stem cells are limited to generating only specific types of cells. For example, hair stem cells will only produce hair, and intestine stem cells will only produce

SciTechDaily
The EMBO JournalJan 5, 2023

Happy New Year 2023!
Our first issue brings:

#Calreticulin conformation changes in cold response

Mammalian #CDC14 #phosphatase controls #stemness exit in #pluripotent cells

#Exosomal #interleukin release via #IQGAP1-mediated #gasdermin-#ESCRT bridging

#Microglial TNFα and cortical protein #phosphorylation during #sleep

...and more:
https://www.embopress.org/toc/14602075/2023/42/1

MzeeDec 23, 2022

Male and Female Stem Cells Derived from One Donor in Scientific First

Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.

https://www.the-scientist.com/news-opinion/male-and-female-stem-cells-derived-from-one-donor-in-scientific-first-70855?utm_content=232700582&utm_medium=social&utm_source=twitter&hss_channel=tw-18198832

#cellbiology #genetics #pluripotent

Male and Female Stem Cells Derived from One Donor in Scientific First

Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.

The Scientist Magazine®