2/
โข The Evolutionary Flow: Traces the progression from genotype through developmental plasticity to the behavioral phenotype. This phenotype is tested by natural selection; successful traits lead to allele frequency shifts in a population.
https://youtu.be/SPWd6CjrJd8
#animals
#ethology
#genotype
#plasticity
#phenotype
#allele
#instinct
#evolution

When synaptic #plasticity depends on more than spike timing alone, the #ClopathRule offers a biologically plausible model incorporating postsynaptic voltage dynamics. This voltage based #STDP model captures #synaptic change features such as frequency dependence and homeostatic stabilization making it useful for simulating #learning and #memory in #NeuralNetworks. Here's a brief introduction to that rule and its applications in #CompNeuro:
๐ https://www.fabriziomusacchio.com/blog/2026-04-14-clopath_rule/
@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.
Huge congrats to Felix and all co-authors! ๐ฅณ
๐ง New paper from the @MaFu55 lab! ๐ฅณ
Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.
๐ https://doi.org/10.1016/j.immuni.2026.03.010
#Neuroscience ๐งช @dzne #3P