PLOS BiologyApr 22, 2025
#Staphylococcus secretes toxins such as PVL to kill immune cells, incl macrophages. This study shows that PVL binds anionic #phospholipids under acidic conditions, targeting lysosomal & mitochondrial #membranes (but not plasma membrane) to promote bacterial escape @PLOSBiology https://plos.io/3RvcArh
Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

Staphylococcus aureus secretes toxins, such as Panton-Valentine leukocidin (PVL), to kill immune cells, including macrophages. This study shows that PVL binds phosphatidic acid and cardiolipin in acidic conditions, targeting lysosomal and mitochondrial membranes (but not the plasma membrane) to promote bacterial escape.

RanjithkJul 29, 2024

Lecithin and phospholipids are essential fatty substances found in the tissues of many living organisms. Lecithin, often extracted from soybeans or egg yolks, is a key source of phospholipids, which are crucial components of cell membranes.

For More info: https://shorturl.at/D4h5w

#Lecithin #Phospholipids #GlobalMarket #HealthIngredients #FunctionalFoods #NaturalIngredients #FoodIndustry #MarketTrends #HealthyLifestyle #FoodInnovation

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Lukas VFN 🇪🇺Jun 28, 2024

Under pressure: How #CombJellies have adapted to life at the bottom of the ocean
https://phys.org/news/2024-06-pressure-jellies-life-bottom-ocean.html

Homeocurvature adaptation of #phospholipids to pressure in #DeepSea invertebrates https://www.science.org/doi/10.1126/science.adm7607

"#Ctenophores have developed unique lipid structures to compensate for the intense pressure that are separate from the ones that compensate for intense cold... so much so that the pressure is actually what's holding their cell membranes together"

Under pressure: How comb jellies have adapted to life at the bottom of the ocean

The bottom of the ocean is not hospitable. There is no light; the temperature is freezing cold; and the pressure of all the water above will literally crush you. The animals that live at this depth have developed biophysical adaptations that allow them to survive in these harsh conditions. What are these adaptations and how did they develop?

Phys.org
Matt WillemsenMar 4, 2024
We May Finally Know How The First Cells on Earth Formed
https://www.sciencealert.com/we-may-finally-know-how-the-first-cells-on-earth-formed #biology #biochemistry #life #protocells #phosphorylation #phospholipids
We May Finally Know How The First Cells on Earth Formed

The story of how life started on Earth is one that scientists are eager to learn.

ScienceAlert
Sterling EricssonMay 2, 2023

The counterpart to nanorobotics is molecular robotics, where instead of building a robotic structure out of metallic components, one uses synthetic phospholipids and other gradient-forming hydrophobic materials.

Scientists at Tohoku University have successfully created self-forming structures scalable to even macro sizes for use in general robotics.

#Robotics #Science #Molecules #Phospholipids #Lipids #Biology #Biochemistry #Biotechnology #Bioengineering #Scicomm

https://pubs.acs.org/doi/10.1021/acs.langmuir.2c02859

Show threadBibiana Prinoth (moved!)Apr 8, 2023

On Earth, EVERY single cell has lipids that protects the inside of the cell. So they are universal biomarkers as we know them. Pablo cares about the tails of the #phospholipids: the #hydrocarbons / #alkanes.

Some of these have been found on Mars!

Lipids are geostable and biomarkers.

The EMBO JournalMar 29, 2023

#Interferon-inducible #phospholipids govern #IFITM3-dependent #endosomal #antiviral immunity

#Phosphatidylinositol(3,4,5)-trisphosphate enhances inhibition of #endocytic viral entry via binding to the intracellular loop of interferon-induced transmembrane protein 3

Anna Kajaste-Rudnitski, Giulia Unali et al

https://www.embopress.org/doi/10.15252/embj.2022112234