Not just passengers: Phages as agents of genetic exchange in fecal #microbiota transplantation.

#Phage ‑mediated gene transfer may shape FMT outcomes by altering gut communities and microbial functions.

#bacteriophage #microbiology #virology #virome

https://davidojcius.blogspot.com/2026/04/not-just-passengers-phages-as-agents-of.html

How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @PLOSBiology https://plos.io/47Aripq

Discovery of human gut #phage -encoded anti-CRISPR proteins unveils diverse mechanisms for phages to evade type II #CRISPR immunity.

Gut #phages encode diverse Acrs; 651 candidates found, including some with dual regulatory & CRISPR‑inhibitory roles.

https://davidojcius.blogspot.com/2026/03/discovery-of-human-gut-phage-encoded.html

#microbioloy

Phage P100 resistance in clinical & foodborne Listeria monocytogenes isolates is associated with adsorption-inhibiting mutations & fitness trade-offs.

Study shows diverse P100 resistance mechanisms in #Listeria & significant serovar‑dependent fitness costs.

https://davidojcius.blogspot.com/2026/02/phage-p100-resistance-in-clinical-and.html #OpenAccess #bacteriophage #phage #food

Molecular basis for anti-jumbo phage #immunity by AVAST type 5.

Avs5 detects an early jumbo‑phage activator and halts infection by rapidly hydrolyzing NAD+.

https://www.sciencedirect.com/science/article/pii/S1097276526000249 #phage #bacteriophage #microbiology

Phage Explorer — Bacteriophage Genome Visualization

Visualize and analyze bacteriophage genomes with color-coded DNA/amino acid sequences, 3D structures, and 40+ analysis tools. Free, open-source, works offline.

Phage Explorer

"The very discovery of phage was the subject of a prolonged dispute between two camps: on one side was Félix d’Herelle,Citation5 the French-Canadian autodidact who first recognize ..."

https://www.tandfonline.com/doi/full/10.4161/bact.20757

#InfectiousDisease #Medicine #phage

A pleasure to have @mfwhite2.bsky.social for our first #BiosciencesInstitute seminar this year and hearing all about #bacterial #phage defences
#AI can now design functional #viruses - not the computer kind, either
Inject this synthetic #phage into #Ecoli and it kills better than the real thing
#Bacteriophages, are viruses that infect bacteria, have been widely studied since their discovery in the early 20th century. The end result of the AI portion of the project was a pool of 302 candidate #genomes, 285 of which were able to generate full genomes. Of those, 16 were found to inhibit growth of E. coli #bacteria.
https://www.theregister.com/2025/09/18/researchers_just_created_a_working/
AI can now design functional viruses – not the computer kind, either

: Inject this synthetic phage into E. coli and it kills better than the real thing

The Register