Mastodawn

This #PLOSBiology Consensus View introduces EEICAT, a framework for assessing how biological invasions affect species, ecosystems, and the environment. It covers 19 types of impacts and aims to help scientists and managers compare and address invasion-driven changes.
#ecology #conservation
https://plos.io/46Q4LVk

Expanding invasive species impact assessments to the ecosystem level with EEICAT

This Consensus View introduces EEICAT, a framework for assessing how biological invasions affect species, ecosystems, and the environment. It covers 19 types of impacts and aims to help scientists and managers compare and address invasion-driven changes.

PLOS Biology Mar 4

Deep learning is increasingly being used in #biology, but evidence suggests that models may not be as generalizable as hoped. Thomas O'Shea-Wheller & Katie Murray outline the scale and severity of the issue, suggesting potential solutions in their #PLOSBiology Perspective.
#AI
https://plos.io/40H9ogJ

Francis Villatoro Feb 27

#PLoSBiology Biomedical and life science articles by female researchers spend longer under review journals.plos.org/plosbiology/... "In the PubMed database (>36.5 million articles) the median amount of time spent under review is 7.4%–14.6% longer for female-authored articles."

Biomedical and life science ar...

Biomedical and life science articles by female researchers spend longer under review

Women are underrepresented in academia, especially in STEMM fields, at top institutions, and in senior positions. This study analyzes millions of biomedical and life science articles, revealing that female-authored articles spend longer under review than comparable male-authored articles, across most fields.

PLOS Biology Feb 12

Improvements to methods should lead to more robust evidence and more rapid advances in knowledge. In their #PLOSBiology Perspective, Marcus Munafò & George Davey Smith look at why this hasn't been the case and what can be done about it. https://plos.io/4rf8mEs

Is scientific reform an unwinnable arms race?

Methodological improvements should, in theory, mean more robust evidence and inference, and more rapid advances in knowledge. However, these methods are often subsequently used in the pursuit of publication for the sake of publication, rather than in the pursuit of knowledge. Can we break this cycle?

PLOS Biology Feb 3

Why are there such big differences between the sexes when it comes to immune responses? This new #PLOSBiology Essay looks at what further research is required to fully determine sex-differential mechanisms in #immunity.
https://plos.io/4ro28S9

Knowledge gaps and research priorities to understand sex differences in immunity

Immunity differs profoundly according to biological sex, leading to sex differences in autoimmunity, infections, cancer and responses to immunotherapy and vaccines. This Essay explores the major areas where further research is required to determine sex-differential mechanisms in immunity.

PLOS Biology Jan 26

Chronic low-grade metabolic #inflammation drives insulin resistance and metabolic dysfunction in #obesity. In this #PLOSBiology Essay, Yun Sok Lee highlights the lesser known beneficial effects of this inflammation and how they can transition into detrimental outcomes. https://plos.io/4sOCOqh

Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation

Chronic low-grade metabolic inflammation (known as metaflammation) drives insulin resistance and metabolic dysfunction in obesity. This Essay discusses the immunometabolic mechanisms underlying metaflammation with a focus on its lesser known beneficial effects and how they can transition into detrimental outcomes.

PLOS Biology Jan 12

Nicole Chapman & Hongbo Chi @stjuderesearch highlight how systems biology approaches are being used to unravel the complex process of metabolic regulation of immune function and advance our understanding of #immunometabolism in our new #PLOSBiology Perspective.
https://plos.io/4aR959z

Multi-omics and perturbation screens as discovery tools in immunometabolism

Metabolic regulation of immune function is a complex and dynamic process. This Perspective highlights how systems biology approaches, including multi-omics profiling and perturbomics screening, are being used to unravel this complexity and advance understanding of immunometabolism.

PLOS Biology Dec 19

2025 was marked by upheaval and uncertainty for many within the life science community. In this Editorial, we reflect on the past year and highlight some of the many research achievements that give us reasons to be thankful. #PLOSBiology #biology #EOY #science #roundup
https://plos.io/4j5T3uh

PLOS Biology Dec 9

Spillover of #influenza A viruses from animals to humans represents a threat to our health. In this #PLOSBiology Perspective, Silke Stertz
@uzh discusses emerging research that suggests some influenza A viruses can enter host cells via MHC-II receptors across species #virology
https://plos.io/4pP3Gnq

A new path to spillover: MHC-II entry of influenza A viruses

Spillover of influenza A viruses from animals to humans represents a threat to our health. This Perspective discusses emerging research that suggests some influenza A viruses can enter host cells via MHC-II across species, reflecting on the consequences that this may have for virus spillover risk.

PLOS Biology Dec 9

The traditional pipeline view of #academia no longer reflects the reality of scientific #careers. In this #PLOSBiology Perspective, Alexandra A-T Weber @eawagresearch reframes success as a network of paths that recognizes excellence in its many forms
https://plos.io/4pSgzx5