I just found this photo of one of the most disgusting preparations of my entire training… PU foam!

First, a highly branched polyester was synthesized from adipic acid, oleic acid, and phthalic anhydride with 1,1,1-tris(hydroxymethyl)propane using PTSA as an acid catalyst. The polycondensation ran for many hours at ~190 °C under nitrogen and vacuum while water was continuously removed as a by-product.

During the reaction, the acid number (determined by titration, mg KOH/g) was monitored until it dropped below 10, with a target around 5. The resulting viscous polyester polyol was then reacted with tolylene-2,4-diisocyanate to produce rigid polyurethane foam.

Chemically interesting.
Visually and olfactorily… slightly traumatic. 🧪😵

#chemistry #organicchemistry #polymerchemistry #polyurethane #polymer #lablife #chemistrylab #chemstudent #polyester #synthesis

Interesting talk by Antonio Echavarren at #Lunteren2026. He talked about the use of gold-carbene catalysis to perform complex and enantioselective transformations in organic synthesis.

https://pubs.acs.org/doi/10.1021/jacsau.3c00159
#Synthesis #OrganicChemistry #Chemistry #Catalysis

Interesting talk by Antonio Echavarren at #Lunteren2026. He talked about the use of gold-carbene catalysis to perform complex and enantioselective transformations in organic synthesis. pubs.acs.org/doi/10.1021/... #Synthesis #OrganicChemistry #ChemSky #Catalysis
Excellent #OrganicSynthesis is the basis of many #ChemBio projects. Nevertheless, we often do not present much of our synthesis. I am excited to be at the Dutch Symposium on Organic Chemistry #Lunteren2026, where synthesis will take the center stage. #ChemSky #OrganicChemistry #Science #Conference

Excellent #OrganicSynthesis is the basis of so many exciting #ChemBio projects. Nevertheless, we often do not present much of the synthesis that we do.

Therefore, I am very happy to be at the Dutch Symposium on Organic Chemistry #Lunteren2026, where organic synthesis will take the center stage for the next 2 days.

#Chemistry #OrganicChemistry #Science #Conference

Chemical Lab Technician

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Did you know that the Beilstein-Institut is a pioneer in (bio)chemistry data standardization?

In close cooperation with the scientific community we set up data standardization projects in #OrganicChemistry, #enzymology and #glycomics.

➡️ https://www.beilstein-institut.de/en/projects/?M=y

#Beilstein75 #STRENDA #MIRAGE #FAIRdata

I am a Trinitarian, if not exactly a good Catholic, so I like to find threes of things. Once you're alert to the ubiquity of three-fold equilibria among fundamental concepts, it's hard not to start seeing triangles in everything…Jewish art and architecture is really good at evoking triplets of things, isn't it? Marvellous. I think of crystals and pyramids and sequences of numbers and all sorts of fun things, when I glance towards the Tree of Life. Kabbalah is closed to me but…c'mon, look at it! of COURSE it's powerful! It's like higher mathematics (cf. the intricate radial and cylindrical symmetries of Muslim art and architecture and its spectacular knowledge of tesselations.)

There is a holy trinity of goat acids. I do not lie! One can speak sensibly, in chemistry, of the goat acids. There are three medium-chain fatty acids, three 'normal' (i.e. straight-chain) alkanoic acids, that are the goat acids.

Caproic acid, hexanoic acid, CH3(CH2)4COOH
Caprylic acid, octanoic acid, CH3(CH2)6COOH
Capric acid, decanoic acid, CH3(CH2)8COOH

All of them have a name which refers to the goat as seen below. The Latin word for goat is capra (and caprea and capriolus and some others, Latin is a bit loosier-goosier with alternate spellings and word-forms than English) and thus supplies the root for all these chemical names. And all these acids and certain compounds of these acids are especially commonplace in goats. Cute widdle bouncy gotes which my esteemed colleague Kaylin Evergreen detests. She is (to me anyway) a priestess of Queen Hera, the formidable matriarch of the Hellenic deities whom I honor as best I can, in whose guidance I have trusted in many lean times and bitter moments. Hera bears among other epithets the name of Ἥρη Αἰγοφάγος, Goat-Eating Hera! Hence I am always getting a bit of stink-eye from Queen Hera about my own…dalliances with gotes. In the past, as it were. oh dear

Anyway! I have had a long-time fascination with this little chemical triplet, which I once remember seeing pop up in a diagram showing how those three acids could be resolved on a liquid chromatographic column. They're "model compounds" indeed: showing that you can resolve the three acids cleanly with your analytical equipment is a good demonstration of the effectiveness of chemical analysis.

They're found among many living things, not just goats; they're among the common lipids of organic life on Earth. Valerian root is another material that tends to be rich in the goat acids and thus valerian has a characteristic stench about it. I happen to regard it as a more or less pleasant smell in moderation (I guess I would) but I will allow as how it's a bit overpowering of other smells. They're just a bit more volatile than other organic acids likely to be found, so…you smell them more.

~Chara of Pnictogen


#goat-acids #goats #chemistry #organic-chemistry #Hera #trinities
Okay, so I had to learn this quickly, and my head is hurting.
#OrganicChemistry #Chemistry

Organic Chemistry, 4th Edition provides a comprehensive yet accessible treatment of all the essential organic chemistry concepts covered in a two-semester course.

Klein's eBook in PDF 👉 https://lttr.ai/AnJvF

#OrganicChemistry