"However, T cell responses to dietary antigen have primarily been characterized using monoclonal T cell receptor (TCR) transgenic systems which do not represent a physiological immune response. Polyclonal CD4+ T cell responses to food, including TCR-specific selection and functional differentiation, remain largely uncharacterized and are critical for understanding mechanisms of tolerance and allergy."
Lockhart, @mucida et al

#Preprint #Immunology #OralTolerance #MucosalImmunology

https://www.biorxiv.org/content/10.1101/2023.04.11.536475v1