Conclusion: In the #Brain 🧠, #Microvasculature is not #Innervated like in #PeripheralTissue. #PrecapillarySphincters and/or #FirstOrderCapillaries are central to #NeurovascularCoupling, which may be enhanced by perpendicular alignment of #NeuronalProcesses (12/15)
#Human🚶‍♀️#Brain 🧠 has similar arrangement of #NeuronalProcesses around #Microvasculature. Shown here for a #FirstOrderCapillary and an #AscendingVenule in the #H01release 3D #ElectronMicroscopy 🔬 dataset: https://tinyurl.com/mvvunjax (11/15)
H01 Release

A Browsable Petascale Reconstruction of the Human Cortex

H01 Release
🐭#Brain #Microvasculature is not #Innervated. But #Parenchymal #NeuronalProcesses arrange perpendicular to #Arteriole direction where #PerivascularSpace exists, while #AscendingVenules do not have this arrangement (10/15)