Check out this #NeuroPreprint thread about phase-dependent excitability in the #Striatum! Really exciting (😁) work by my colleague @manishm in the #vanDerMeerLab ⬇️

#Neuroscience #NeuroMouse #Optogenetics

From: @manishm
https://neuromatch.social/@manishm/111865248137896127

Some very nice #PlaceCells and #GridCells in this Virtual Reality experiment in #NeuroMice!
#NeuroPreprint from the #ChenLab:

Visual boundary cues, alone, can anchor place and grid cells in virtual reality

The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice

”ChrOnic Multimodal imaging and Behavioral Observation”

”we demonstrate how the COMBO window facilitates the combination of optogenetics, fUS and electrophysiology in the same [head-fixed] animals”

#NeuroPreprint #NeuroMethods

#NeuroPreprint, reanalysis of #GridCell firing in a circular track originally from the #SargoliniLab / #JacobLab:

From: @biorxivpreprint
https://biologists.social/@biorxivpreprint/111072182270882574

Lots of cool findings about #FOS in this new paper, might change the interpretation of a lot of existing studies!

Especially:

“We propose that FOS does not primarily encode a neuron’s own spike frequency but indicates repeated participation in highly synchronized activity, e.g. #SWR .”👀

Neuronal FOS reports synchronized activity of presynaptic neurons

#OertnerLab #Neuroscience #NeuroPreprint

Interesting #NeuroPreprint about separating “motor” and “cognitive” variables in neural analyses, which should really be given more attention in all studies IMO:
Separating cognitive and motor processes in the behaving mouse

by #EconomoLab

#Need2Read

Another cool #NeuroPreprint (broadly speaking: it’s on #Navigation performance), from #SpiersLab (@hugospiers):
Video gaming, but not reliance on GPS, is associated with spatial navigation performance
I am intrigued by the difference in sample numbers: “n = 822, 280 men, 542 women”? Is that a typo?
And also this:

“There was a significant association between weekly hours of video gaming and navigation performance which was not moderated by gender. After accounting for video game experience, gender was no longer significantly associated with navigation performance.”
Is gender a factor or not? 🤔
#Gaming #Need2Read

Interesting looking new #Hippocampus #NeuroPreprint from #StarkLab:

Local activation of CA1 pyramidal cells induces theta phase precession

“The findings are incompatible with precession models based on inheritance, spreading activation, dual-input, or inhibition-excitation summation. Thus, a precession generator resides locally within CA1”

#PhasePrecession #Optogenetics #Need2Read

#NeuroPreprint #DerdickmanLab #PlaceCells #TimeCells #Hippocampus

Time or distance: predictive coding of Hippocampal cells

We show that the type of experiment determined the cells’ encoding, such that in fixed-distance experiments distance-encoding cells dominated, while on fixed-time experiments time-encoding cells dominated.

Seems very interesting! But is it surprising? Place cells are known to encode what is consistent and disregard what is not… 🤔
#Need2Read

Edit: typo

#NeuroPreprint #Hippocampus
Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine

#NeuroMice #CognitiveMap #CalciumImaging #SprustonLab #Modeling (#Need2Read)