🧪 August’s most-read Biochemistry paper presents an alternative platform for #nanobody discovery using phage-displayed synthetic libraries: https://elifesciences.org/articles/105887?utm_source=mastodon&utm_medium=social&utm_campaign=submissions_organic&utm_content=top_paper

Have a paper people should see? See what our Editors look for: https://elifesciences.org/about/aims-scope?utm_source=mastodon&utm_medium=social&utm_campaign=submissions_organic&utm_content=top_paper#biochemistry-and-chemical-biology

Eine gute Nachricht.

https://idw-online.de/de/news857576

#medizin #herpes #nanobody #uh

🤖 Can algorithms outsmart evolution to create therapies humans never imagined?

🔗 Computational nanobody design through deep generative modeling and epitope landscape profiling. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.052

📚 CSBJ: https://www.csbj.org/

#Nanobody #AI #DeepLearning #ProteinDesign #DrugDiscovery #ComputationalBiology #GenerativeAI #Immunotherapy #COVID19 #SARSCoV2 #Omicron #AntibodyEngineering #SyntheticBiology #TranslationalResearch

🦙 Nanobody neutralizes deadly Nipah and Hendra viruses in lab tests

https://phys.org/news/2025-07-nanobody-neutralizes-deadly-nipah-hendra.html

#medicine #healthcare #nanobody #drugs #pharmacology #disease #virus

#Nanobody neutralizes deadly #Nipah and #Hendra #viruses in lab tests

https://phys.org/news/2025-07-nanobody-neutralizes-deadly-nipah-hendra.html

"The Virtual Lab: AI Agents Design New SARS-CoV-2 Nanobodies with Experimental Validation"

We demonstrate the power of the Virtual Lab by applying it
to design nanobody binders to recent variants of SARS-CoV-2, which is a challenging,
open-ended research problem that requires reasoning across diverse fields from biology to
computer science.

https://www.biorxiv.org/content/10.1101/2024.11.11.623004v1

#COVID #AIMedicine #nanobody #VirtualLab

#Influenza A Virus #H7 #nanobody recognizes a conserved immunodominant epitope on #hemagglutinin head and confers heterosubtypic #protection

Source: BioRxIV, AbstractInfluenza remains a persistent global health challenge, largely due to the virus continuous antigenic drift and shift, which impede the development of a universal vaccine. To address this, the identification of broadly neutralizing antibodies and their epitopes is crucial. Nanobodies, with their unique…

https://etidioh.wordpress.com/2024/11/01/influenza-a-virus-h7-nanobody-recognizes-a-conserved-immunodominant-epitope-on-hemagglutinin-head-and-confers-heterosubtypic-protection/