πŸ’Š What makes a good RNA-targeting drug?

Molecular biologist at the UG Danny Incarnato shows that small molecules that bind to RNA only rarely affect its function, while molecules that change RNA structure have a bigger effect.

His team's findings were published in Nature Communications.

Curious? Read more πŸ‘‡
πŸ”— https://www.rug.nl/fse/news/highlighted-papers/2026/study-shows-how-to-identify-drugs-altering-rna-structure-and-function

πŸ§ͺ #SciComm #ScienceNewsroom #molecular #biology #genetics #biochemistry #chemistry #scientistsOnMastodon @universityofgroningen @nature

πŸ…Can we also blame #GA for us missing #TomatoTuesday?
πŸ…Xu et al. investigate the #molecular basis of cut-budding in #tomato, specifically, the role of GROWTH-REGULATING FACTOR1 & its association with gibberellin signaling.
πŸ… https://doi.org/10.1111/jipb.70219
@WileyLifeSci
#PlantSci #JIPB #botany
Researchers identified the precise structural organization of the #molecular protein landscapes within the photosynthetic membranes of plant leaves.
#PlantBiology #Biophysics #QuantitativeBiology #Botany #sflorg
https://www.sflorg.com/2026/03/bot03102601.html
New study sheds light on protein landscape crucial for plant life

The discovery provides a new view of the molecular engine that converts sunlight into bioenergy

🩹During healing, #plant cells release endogenous elicitor peptides to facilitate #immunity.
🌿New work from Claus et al. reveals that endocytosis of the damage-associated #molecular pattern receptor PEPR1 is BAK1 dependent.
πŸ”“β¬‡οΈ
πŸ”—https://doi.org/10.1111/jipb.70083
@WileyLifeSci
#PlantSci #botany

How #sweet it is!
(no, really...how sweet?)

🍊In new work on the satsuma mandarin, Zeng et al. explore the #molecular basis of drought-induced sucrose accumulation and present regulatory targets for improving #fruit quality.

https://doi.org/10.1111/jipb.70076
@WileyLifeSci
#PlantSci #JIPB #botany

πŸ“’ The IUPAP Early Career Scientist Prize in Atomic, Molecular and Optical Physics 2026 is open for nominations.

πŸ‘‰ https://eps.org/iupap-early-career-scientist-prizein-atomic-molecular-and-optical-physics-2026/

#physics #earlyCareer #prize #atomic #molecular #optical #science #nomination

#Fashion week...#plantscience style!πŸ˜ŽπŸ’…
Check out these #molecular models as Wang et al. provide key enzymatic tools and #genetic elements for #genome-guided metabolic engineering of saponin pathways in the #medicinal #plant Dioscorea.
https://doi.org/10.1111/jipb.70089
@WileyLifeSci
#JIPB #Botany #FreeAccess
Imaging technique captures ultrafast electron and atom dynamics in chemical reactions

During chemical reactions, atoms in the reacting substances break their bonds and re-arrange, forming different chemical products. This process entails the movement of both electrons (i.e., negatively charged particles) and nuclei (i.e., the positively charged central parts of atoms). Valence electrons are shared and re-arranged between different atoms, creating new bonds.

Phys.org

New publication in #molecular #psychiatry together with Pharmacology at @uniinnsbruck

We present the first functional analysis of patient-derived #stemcells #neurons and #organoids carrying a CACNA1D variant.

If you want to know more, follow the link:
https://www.nature.com/articles/s41380-025-03429-8

#science #research