A comprehensive atlas of full-length Arabidopsis eccDNA populations identifies their genomic origins and epigenetic regulation.
#ExtrachromosomalCircularDNA #eccDNA #Transposons #Arabidopsis #MethylationMutants #LongReadSequencing
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003275
A comprehensive atlas of full-length Arabidopsis eccDNA populations identifies their genomic origins and epigenetic regulation
Previous studies of extrachromosomal circular DNA (eccDNA) in plants are based on short-read sequencing and cannot efficiently identify their full-length, generated from transposable elements. This study uses long-read sequencing to obtain a comprehensive map of full-length eccDNAs from Arabidopsis and identifies their genomic origins and epigenetic regulation.