StructBiolCommunicationsIn silico removal of an N-terminal tag on Onchocerca volvulus macrophage migration inhibitory factor-1 exposes a large cavity that can be used for drug discovery.#MacrophageMigrationInhibitoryFactor1 #RiverBlindness https://t.co/VzZXUlF5nD
Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1
N-terminally hexahistidine-tagged O. volvulus macrophage migration inhibitory factor-1 has a unique jellyfish-like structure with the prototypical macrophage migration inhibitory factor trimer as the `head' and a C-terminal extension as the `tail'.