π€ What happens when we train AI to see through the noise of cryo-EM imaging?
π A labeled dataset for AI-based cryo-EM map enhancement. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.041
π CSBJ: https://www.csbj.org/
#AI #CryoEM #StructuralBiology #DeepLearning #OpenScience #ProteinStructures #MolecularBiology #Macromolecules #BigData
26-Sep-2025
What is the significance of the evolution from #chiral molecular #macrocycles to chiral topological macrocycles?
https://www.eurekalert.org/news-releases/1099922
#science #chemistry #selfAssembly #nanoworld #macromolecules '#supramolecularChemistry #chirality
A novel strategy was designed for guiding supramolecular macrocycles into nanoscale chiral topological toroids, establishing hierarchical self-assembly pathways for advanced chiroptical materials
An international team of researchers led by the University of Bern has used observation-based computer modelling to find an explanation for how macromolecules can form in a short time in disks of gas and dust around young stars. These findings could be crucial for understanding how habitability develops around different types of exoplanets and stars.
Does accumulation of #macromolecules in the highly protein-rich #mitochondrial matrix regulate solute diffusion and biochemical reactions?
Using FRAP analysis of #organelle-targeted fusion peptides, Werner Koopman and colleagues report macromolecular crowding as a stress-dependent determinant of matrix mobility and viscosity
Referenced link: https://phys.org/news/2022-09-theory-upends-macromolecules-self-assemble.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-09-theory-upends-macromolecules-self-assemble.html
Originally posted by Phys.org / @[email protected]: https://twitter.com/physorg_com/status/1574497259529682952#m
New theory upends what we know about how charged #macromolecules self-assemble @umassamherst @PNASNews https://pnas.org/doi/full/10.1073/pnas.2204163119 https://phys.org/news/2022-09-theory-upends-macromolecules-self-assemble.html
In a discovery with wide-ranging implications, researchers at the University of Massachusetts Amherst recently announced in the Proceedings of the National Academy of Sciences that uniformly charged macromoleculesβor molecules, such as proteins or DNA, that contain a large number of atoms all with the same electrical chargeβcan self-assemble into very large structures. This finding upends our understanding of how some of life's basic structures are built.
CSBJ
michael
UniversitΓ€t Bern
The EMBO Journal
Phys.org