Presenting a model for proteasome condensate formation in which shuttle factors play a critical role. ↔ 💧

Kenrick Waite and team #KUMedCenter show that shuttling factors Rad23 and Dsk2 contribute to the localization of proteasomes in condensates - a process that Ddi1 counteracts. #preprint

#preLight by Aniruddha Das 👉 https://prelights.biologists.com/highlights/proteasome-condensate-formation-is-driven-by-multivalent-interactions-with-shuttle-factors-and-k48-linked-ubiquitin-chains/

#proteasome #yeast #condensate

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains - preLights

Shuttling factors Rad23 and Dsk2 contribute to the localization of proteasomes in condensate, a process that Ddi1 counteracts.

preLights