What confuses me the most about HRT for menopause is the assertion that adding estrogen back is DANGEROUS, yet I spent 19 years fighting to get sterilized even though pregnancy would have increased my estrogen levels to approximately 100x the levels of a non pregnant person by week 32.

So according to every OBGYN I have seen in my whole life MHT= scary dangerous blood clots!! but 100x that amount of estrogen from pregnancy = no big deal because it’s my duty to stroke out so we have more kids for the wealthy and religious to molest.

I should stop reading things like this because they just piss me off. And I guess I am still traumatized from misogynistic medical neglect.

“Women's Health Opportunity for Improved Menopausal Hormone Therapy Prescribing” ⬇️
https://jamanetwork.com/journals/jama/fullarticle/2846683

#HRT #menopause #MHT #JAMA #estrogen (The only “drug” I have considered seeking from the street. Ever. And I take oxy and adderall.)

I don’t actually believe this because I have been experiencing adderall shortages regularly since 2011, but I guess it’s nice to see they aren’t trying to blame it on “overprescribing” when people who didn’t have access to mental healthcare got access because of telemedicine.

From the link:
Although the researchers noted that public debate about the ADHD drug shortage had largely centered around prescribing trends and Drug Enforcement Administration quotas, their findings suggest that supply chain disruption may have been a major contributor. They added that this highlights “the vulnerability of US pharmaceutical manufacturing to international supply chain disruptions” and underscores “the need for policies that strengthen supply chain resilience.”

ADHD Drug Shortage Cause Identified

https://jamanetwork.com/journals/jama/fullarticle/2847798

#jama #adhd #adderall #DrugShortage

ADHD Drug Shortage Cause Identified

The shortage of attention-deficit/hyperactivity disorder (ADHD) medication in the US from 2022-2023 may have been caused by international supply chain disruptions, a study found.

日本の医学研究、ヤバすぎ。撤回論文の偏りが異常。特に「superretractor」6人のうち5人が日本人…😱 #医学研究 #撤回論文 #JAMA

What to Know About Cicada, or BA.3.2, the Latest SARS-CoV-2 Variant Under Monitoring
https://jamanetwork.com/journals/jama/fullarticle/2848071

#JAMA #covid #cicada

What to Know About the Cicada SARS-CoV-2 Variant

This JAMA Medical News article discusses the unusual trajectory of BA.3.2, the most recent version of SARS-CoV-2 to be designated a Variant Under Monitoring by the World Health Organization.

More #teens are getting hooked on gambling, often undetected #Gambling's soared in the US since 2018 #SCOTUS ruling allowing states to legalize #SportsBetting, going from 1 state in 2018, when USians spent $4.9B/yr, to 38 states & $121B/yr in 2024 & 2023 respectively, per #JAMA. The full story:

More teens are getting hooked ...

More #teens are getting hooked on gambling, often undetected thanks to #OnlineGambling

#Gambling's soared in the US since 2018 #SCOTUS ruling allowing states to legalize #SportsBetting, going from 1 state in 2018, when USians spent $4.9B/yr, to 38 states & $121B/yr in 2024 & 2023 respectively, per #JAMA.

There's more to the story:
https://www.npr.org/2026/04/05/nx-s1-5762276/teens-getting-hooked-on-gambling-sports-betting

Embracing Bayesian Methods in Clinical Trials

This Perspective discusses the importance of the US Food and Drug Administration’s draft guidance on the use of bayesian methods in clinical trials because it underscores its commitment to modernizing clinical research.

Enes Erul MD (@ErulEnes)

JAMA 편집자 노트는 AI가 학술 작업에 일상적으로 사용되고 있음을 지적합니다. JAMA Network에 제출된 원고에서 AI 사용 공개 비율이 약 2년간 1.7%에서 6.0%로 증가했으며, AI 사용의 약 68%는 주로 언어 다듬기(문장/문법 개선)에 해당합니다. 편집자는 채택 속도에 맞춘 투명성·공개 기준 정비의 필요성을 강조합니다.

https://x.com/ErulEnes/status/2027803449048347018

#jama #academicpublishing #aiusage #aitransparency

Enes Erul MD (@ErulEnes) on X

JAMA Editor’s Note felt like a mirror: AI is now routine in academic work. In JAMA Network submissions, AI-use disclosure rose 1.7%→6.0% in ~2 years; most use is language refinement (~68%). Transparency must keep pace with adoption. 🤖📄🧪 #AI @GlopesMd @DeryaTR_ @jnkath

X (formerly Twitter)

the brewhaha man came to town
staph on my knee is starting to resolve - starting to recover faster - every 3 mos i get nailed

#moderate drinking as a coping mechanism #jama

I guess there was a study that claimed Metformin wasn’t helpful with covid in people who are not obese. This looks like a good rebuttal with some valid points about why the study wasn’t so good.

“Metformin Therapy for Patients With COVID-19 Without Obesity”
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2842942

#metformin #JAMA #covid #LongCovid