Wondering if you have Influenza A or B? Learn about the typical duration of symptoms for each and get a clear comparison to understand your illness better.
https://www.bondhuplus.com/read-blog/180408_influenza-a-vs-b-how-long-do-symptoms-really-last.html

#InfluenzaA #InfluenzaB #FluSymptoms #FluSeason #HealthTips #ViralIllness #SymptomDuration #FluComparison #KnowYourFlu

Outbreak: #InfluenzaB (not subtyped) + #Parainfluenza Virus
Facility: Villa Minto
Facility Type: LTC Home
Unit/Floor/Area: Facility Wide
Location: #Cochrane #Ontario
Date: 2025-05-05

Public Health Unit: Northeastern Public Health
Facility Tracking Hash: #NEPH0010 (formerly #POHU0002)
PHU Tracking Hash: #OnObNEPH (formerly #OnObPOHU)

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Outbreak: #InfluenzaB + #Parainfluenza Virus
Facility: Extendicare Timmins
Facility Type: LTC Home
Unit/Floor/Area: Facility Wide
Location: #Timmins #Ontario
Date: 2025-04-19

Public Health Unit: Northeastern Public Health
Facility Tracking Hash: #NEPH0002
PHU Tracking Hash: #OnObNEPH

Click or follow tracking hashtags to see data for individual facilities or a specific public health unit.

Kämpfe seit ein paar Tagen mit #Grippe bzw. #Influenza. Gerade abends geht das #Fieber immer wieder ordentlich hoch. 🤒🥵

Hat jemand vielleicht ein paar weitere Tipps außer #Ibuprofen, #Paracetamol und #Wadenwickel?

#Grippewelle #Grippeimpfung #InfluenzaA #InfluenzaB #Viren #Influenzawelle #Gesundheit #Infektion #Infektionskrankheit

Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad #Neuraminidase #Inhibition by #Human #Antibodies

Source: BioRxIV, https://www.biorxiv.org/content/10.1101/2024.11.27.625426v1?rss=1

Abstract
Influenza has been responsible for multiple global pandemics and seasonal epidemics and claimed millions of lives. The imminent threat of a panzootic outbreak of avian influenza H5N1 virus underscores the urgent need for pandemic preparedness and effective countermeasures, including monoclonal antibodies (mAbs). Here, we characterize human mAbs that target the highly conserved catalytic site of viral neuraminidase (NA), termed NCS mAbs, and the molecular basis of their broad specificity. Cross-reactive NA-specific B cells were isolated by using stabilized NA probes of non-circulating subtypes. We found that NCS mAbs recognized multiple NAs of influenza A as well as influenza B NAs and conferred prophylactic protections in mice against H1N1, H5N1, and influenza B viruses. Cryo-electron microscopy structures of two NCS mAbs revealed that they rely on structural mimicry of sialic acid, the substrate of NA, by coordinating not only amino acid side chains but also water molecules, enabling inhibition of NA activity across multiple influenza A and B viruses, including avian influenza H5N1 clade 2.3.4.4b viruses. Our results provide a molecular basis for the broad reactivity and inhibitory activity of NCS mAbs targeting the catalytic site of NA through substrate mimicry.

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#aH1n1 #aH5n1 #abstract #avianInfluenza #AVIANINFLUENZA #birdFlu #h5n1 #health #influenzaB #monoclonalAntibodies #news #research #SEASONALINFLUENZA