rexiSep 9, 2025

https://medicalxpress.com/news/2025-09-rapamycin-linked-dna-resilience-aging.html

(boomer bolstering )

Originally developed for organ transplantation to prevent immune rejection, previous research has found that, at non-#immunosuppressive doses, #rapamycin can mitigate cellular #senescence.

"rapamycin provides direct #genomicprotection in human immune cells and may support healthy aging, offer benefits after clinical #radiationexposure, and could even address risks from #cosmicradiation during extended #spacetravel."

Rapamycin linked to DNA damage resilience in aging human immune cells

University of Oxford-led research finds low-dose rapamycin functions as a genomic protector in aging human immune cells, lowering DNA damage.

Medical Xpress
John Vaccaro (johniac)Mar 10, 2025

SciTech Chronicles. . . . . . . . .Mar 10th, 2025

https://bit.ly/stc031025

#cancer #cardiovascular #saturated #unsaturated #fMRI #prefrontal #frontoparietal #ganglia #fMRI #prefrontal #frontoparietal #ganglia #dopamine #iPSCs #dopaminergic #immunosuppressive #theoretical #voltage #Hydrogen #Oxygen

SciTech Chronicles. . . . . . . . .Mar 10th, 2025

Everybody Hurts... Sometime. Vol II No 62 195 links Curated More plant oils, less butter could lead to better health. https://www.sciencedai...

Matt WillemsenNov 12, 2023
Meta-Analysis of Postcancer Use of Immunosuppressive Therapies Shows No Increase in Cancer Recurrence Risk
Patients with immune-mediated diseases and a history of malignancy had similar rates of cancer recurrence whether or not they were receiving immunosuppressive treatments
https://www.medscape.com/s/viewarticle/998366 #MetaAnalysis #Postcancer #Immunosuppressive #Therapies
Meta-Analysis of Postcancer Use of Immunosuppressive Therapies Shows No Increase in Cancer Recurrence Risk

Patients with immune-mediated diseases and a history of malignancy had similar rates of cancer recurrence whether or not they were receiving immunosuppressive treatments.

Medscape
Scientific FrontlineOct 26, 2023
Clostridioides difficile (C. diff) #intestinal #infections can cause severe, debilitating #diarrhea in patients who are hospitalized or on #immunosuppressive therapies. The infections can be very hard to eradicate
#Microbiology #Medical #sflorg
https://www.sflorg.com/2023/10/mcb10262301.html
Unconventional Approach to C. Diff

Lab experiments support treating inflammation rather than bacteria

PLOS BiologyMay 6, 2023
How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
Dismantling the tumoral cloak of self-protection

The mechanisms by which tumors promote hematopoiesis outside the bone marrow have been the subject of intense interest. This Primer explores a new PLOS Biology study that provides new insight into the mechanisms underlying this process, and may hold the key to disrupting generation of the immunosuppressive tumor microenvironment.

PLOS BiologyMay 5, 2023
How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
Dismantling the tumoral cloak of self-protection

The mechanisms by which tumors promote hematopoiesis outside the bone marrow have been the subject of intense interest. This Primer explores a new PLOS Biology study that provides new insight into the mechanisms underlying this process, and may hold the key to disrupting generation of the immunosuppressive tumor microenvironment.

PLOS BiologyMay 5, 2023
How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
Dismantling the tumoral cloak of self-protection

The mechanisms by which tumors promote hematopoiesis outside the bone marrow have been the subject of intense interest. This Primer explores a new PLOS Biology study that provides new insight into the mechanisms underlying this process, and may hold the key to disrupting generation of the immunosuppressive tumor microenvironment.

DeborahApr 21, 2023
This piece from author Amy Silverstein on the highs and low of being a #heart transplant recipient. Amy is absolutely correct when she calls out the lack of recent progress in the development of newer #immunosuppressive agents, which might have far less in the way of problematic side effects for #patients #MedMastodon #physicians https://www.nytimes.com/2023/04/18/opinion/heart-transplant-donor.html?smid=tw-share
Opinion | My Transplanted Heart and I Will Die Soon

Organ transplantation is mired in stagnant science and antiquated, imprecise medicine that fails patients and organ donors.

The New York Times