Why do preterm neonates struggle to control sepsis?
“This study provides insight into how Krüppel-like factor 2 (KLF2) is involved” and shows that “KLF2 is a promising target in successfully treating newborns with sepsis.”
#preLight from Sydney Call & Sahan Senanayaka #ImmunobiologyUA ! ⬇️ 👀
#immunology #sepsis #biology #therapeutics #endotoxemia #inflammasome
Blurring the lines between retrotransposons & viruses!
sORF2 enables envelope-independent, direct cell-to-cell transmission of retrotransposons in Drosophila, challenging our understanding of mobile genetic elements.
#preLight from Ally Simpson & Alyss Humphrey #ImmunobiologyUA ! ⬇️ 👀
👉 https://prelights.biologists.com/highlights/direct-cell-to-cell-transmission-of-retrotransposons/
#genetics #immunobiology #drosophila #retrotransposons #TEs #viruses
Defence mechanism inception!
Listeria prophages protect their host bacteria with anti-phage systems, leaving them susceptible to their own defence systems - read how this may actually be an evolutionary advantage!
#preLight from Briana Guzman, Noah Franz #ImmunobiologyUA ! ⬇️ 👀
#microbiology #immunobiology #bacteria #infection #phages #prophages
Led by Samuel Campos, the IMB565 class #ImmunobiologyUA has preLighted recent #immunology preprints.
“Resident Killers: Tonsil resident NK cells show potential against early HIV-1 infection.” #preprint from David Perea, Maria Buzon & team
#preLight prepared by Sukirti Shivpuri, Jared Alvarez & Vanessa Brizuela ⬇️
Viperin and viral hemorrhagic septicemia virus take advantage of feedback regulation through competing protein degradation pathways. #preprint
Prepared by Paige Sandoval, Fahmida Alam & Hriday Sutradhar- another preLight from the IMB565 class #ImmunobiologyUA ! 🙌 ⬇️ 👀
#preLight 👉 https://prelights.biologists.com/highlights/feedback-loop-regulation-between-viperin-and-viral-hemorrhagic-septicemia-virus-through-competing-protein-degradation-pathways/
Phage therapy FTW!💥 But be warned, the vibes that these efficient bacterial killers have with human cells can vary!🧫 Get the scoop on these micro-warriors!💊 #preprint #PhageRevolution
preLight post from Riley Hellinger & Yash Sharma #ImmunobiologyUA ! ⬇️ 👀
#preLight: https://prelights.biologists.com/highlights/lytic-bacteriophages-interact-with-respiratory-epithelial-cells-and-induce-the-secretion-of-antiviral-and-proinflammatory-cytokines/
Phage therapy FTW!💥 But be warned, the vibes that these efficient bacterial killers have with human cells can vary!🧫 Get the scoop on these micro-warriors!💊 #PhageRevolution
Recent #preprint from the lab of Jacqueline Kimmey provides compelling insights into the interactions between #microbes and circadian rhythm that is understudied and overlooked.
Another preLight from the IMB565 class #ImmunobiologyUA !
This post was prepared by Fadi Sayegh & Mohammed Jalloh ⭐
#preLight 👉 https://prelights.biologists.com/highlights/streptococcus-pneumoniae-augments-circadian-clock-gene-expression-in-zebrafish-cells/
TBDisseminated: the importance of PPARy and lipid biogenesis in disseminated tuberculosis infection.
Another preLight from the IMB565 class #ImmunobiologyUA !
Nicholas Cusick, Sloane McVicker & Sydney Verdugo cover a preprint from Rajesh Gokhale & team.
#preLight 👉 https://prelights.biologists.com/highlights/ppar%ce%b3-mediated-enhanced-lipid-biogenesis-fuels-mycobacterium-tuberculosis-growth-in-hepatocytes/
Led by Samuel Campos, the IMB565 class #ImmunobiologyUA has preLighted recent preprints in #microbiology & #immunobiology
preLight prepared by Jennifer Uhrlaub, Christina Arnoldy & Anh Evy Nguyen
“A mycovirus could be the Achilles Heel of Aspergillus fumigatus; curing it could cure us.” #preprint #ShlezingerLab ⬇️ 👀
#preLight 👉 https://prelights.biologists.com/highlights/aspergillus-dsrna-virus-drives-fungal-fitness-and-pathogenicity-in-the-mammalian-host-v2/
Coxiella burnetii demonstrates a strategy to effectively evade the #ImmuneSystem by inhibiting IL-17-induced oxidative stress in macrophages. #Qfever
#preLight by Abigail Page & Farhana Afrin Mohona - IMB565 #ImmunobiologyUA
#preLight 👉 https://prelights.biologists.com/highlights/coxiella-burnetii-actively-blocks-il-17-induced-oxidative-stress-in-macrophages/
Coxiella burnetii, the pathogen that causes Q fever, demonstrates a strategy to effectively evade the immune system by inhibiting the IL-17-induced oxidative stress in macrophages. preLight Authors: Abigail Page & Farhana Afrin Mohona
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