Researchers enable non-line-of-sight imaging using consumer LiDAR, allowing sensors to visualize objects hidden from direct view
A new multi-frame fusion strategy allows consumer-grade LiDAR sensors to image objects hidden from their direct field of view.
https://newsnews.ai/article/consumer-lidar-hidden-object-imaging
🧠📐 Kaltenecker et al present #MouseMapper, that combines whole-body tissue clearing, #lightsheet #imaging and foundation-model-based #DeepLearning to quantify nerves, immune cells & 31 organs/tissues across entire #mouse bodies.
Applied to diet-induced #obesity, it revealed reduced nerve density, infraorbital trigeminal nerve defects, impaired whisker sensing, & body-wide inflammatory CD68⁺ immune-cell clustering.
To capture this local heterogeneity, the authors developed a #multiphoton #FLIM approach with the Na⁺ indicator ING-2 and #astrocyte labeling, enabling quantitative Na⁺ measurements in individual #astrocytes and their processes. This is important because astrocytic Na⁺ is not just a bulk somatic variable. It varies locally across branches and subdomains, where K⁺ uptake and #glutamate-linked Na⁺ influx are regulated.
🧠 New paper by Carneiro-Nascimento et al: awake #invivo #2p #CalciumImaging reveals diverse #CalciumDynamics in #meningeal #macrophages during cortical spreading depolarization (CSD), an aberrant #brain #hyperexcitability event linked to #migraine, #stroke, and #traumatic brain injury.
📝 https://doi.org/10.7554/eLife.109888
#Neuroimmunology #Neuroscience #imaging @eLife https://fediscience.org/@eLife/116605475951455191