New review out: "Metabolic Modeling of Host–Microbe Interactions". In the article, we:
Outline strategies for coupling host and microbial genome scale metabolic models #GEM
Highlight successful applications revealing #HostMicrobiome cross-feeding
Discuss challenges (regulation, dynamics, model validation) and possible solutions
Outline fields which are worthwhile exploring from a #SystemsBiology perspective

https://doi.org/10.1016/j.csbj.2025.10.006

#MetabolicModeling #MicrobiomeScience #ComputationalBiology