Italian News by RSSMar 31

IlPescara: Terapie ematologiche nei distretti sanitari e le Case di comunità e non più in ospedale: sì alla proposta di D'Addazio (FdI)

Sì unanime in commissione Sanità alla mozione presentata dal consigliere regionale FdI Leonardo D’Addazio perché le terapie sottocutanee e stabilizzate che si somministrano ai pazienti oncologici, vengano effettuate nei presidi locali così che non ci si debba più spostare verso gli ospedali. Un...

Hematological therapies in healthcare districts and community centers and not in hospitals: yes to D’Addazio’s (FdI) proposal.

Yes, unanimously in the Health Commission on the motion presented by regional councillor FdI Leonardo D’Addazio, because subcutaneous and stabilized therapies administered to oncological patients should be carried out at local facilities so that patients no longer have to travel to hospitals.

#Hematological #theHealthCommission

https://www.ilpescara.it/politica/mozione-rafforzamento-rete-ematologica-d-addazio-fdi.html

Terapie ematologiche nei distretti sanitari e le Case di comunità e non più in ospedale: sì alla proposta di D'Addazio (FdI)

Evitare gli spostamenti negli ospedali e garantire il servizio di prossimità: questo l'obiettivo della mozione del consigliere regionale, approvata all'unanimità dalla commissione Sanità...

IlPescara
SICB journals(ICB & IOB)Nov 28, 2023

IOB

"#Behavioral state is linked with physiological states that shows tradeoff & life history traits. This study is a small effort to know this incredible #species."
By
Nimra et al

https://doi.org/10.1093/iob/obad027

#birds #biology #adaptation #biology #science #hematological

Seasonal Changes in Hematological Parameters in House Sparrows of Subtropical Pakistan

Synopsis. House sparrow is a globally adaptive bird. The way this creature adapted to all areas of the world, having different selection pressures, is interesti

OUP Academic
SICB journals(ICB & IOB)Aug 4, 2023

Iob

Fresh ink!!
#Seasonal Changes in #Hematological Parameters in House #Sparrows of #Subtropical #Pakistan

by Nimra, Kayani, Irfan, Ahmed

https://doi.org/10.1093/iob/obad027

#birds #orinthology #sciencetwitter #biologists #organisms

Seasonal Changes in Hematological Parameters in House Sparrows of Subtropical Pakistan

Synopsis. House sparrow is a globally adaptive bird. The way this creature adapted to all areas of the world, having different selection pressures, is interesti

OUP Academic
Daniel Auclair, PhDNov 10, 2022

Human bone marrow organoids for disease modelling, discovery and validation of therapeutic #targets in #hematological malignancies

https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-22-0199/710534/Human-bone-marrow-organoids-for-disease-modelling

Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies

Abstract. A lack of models that recapitulate the complexity of human bone marrow has hampered mechanistic studies of normal and malignant hematopoiesis and the validation of novel therapies. Here, we describe a step-wise, directed-differentiation protocol in which organoids are generated from iPSCs committed to mesenchymal, endothelial and hematopoietic lineages. These 3-dimensional structures capture key features of human bone marrow – stroma, lumen-forming sinusoids and myeloid cells including pro-platelet forming megakaryocytes. The organoids supported the engraftment and survival of cells from patients with blood malignancies, including cancer types notoriously difficult to maintain ex vivo. Fibrosis of the organoid occurred following TGFβ stimulation and engraftment with myelofibrosis but not healthy donor-derived cells, validating this platform as a powerful tool for studies of malignant cells and their interactions within a human bone marrow-like milieu. This enabling technology is likely to accelerate discovery and prioritization of novel targets for bone marrow disorders and blood cancers.

American Association for Cancer Research