♻️ Second-Line Therapy for H. pylori

🚫 Don’t reuse clarithromycin or levofloxacin.

🔹 Choose rescue regimens based on local resistance or susceptibility testing.

✅ Options: 10–14 day Bismuth Quadruple Therapy (BQT) or Levofloxacin-based Quadruple (guided use only).
#GastroAGI #HPylori #AntibioticStewardship

First-Line Therapy for H. pylori

👉 Bismuth quadruple therapy (BQT) = preferred empiric regimen, esp. where clarithromycin resistance is high.

✅ PPI + Tetracycline + Metronidazole + Bismuth

🔹 PCAB (vonoprazan)–based regimens = effective alternatives.

🚫 Avoid levofloxacin first line.
#GastroAGI #HPylori #GastroUpdate

H. pylori Screening – Population Strategy Non-invasive tests preferred:

🔹 13C-UBT & Monoclonal HpSA (H.Pylori Stool Antigen) ✅

🔹 13C-UBT: Sensitivity 95%, Specificity 95%

🔹 HPSA: Sensitivity 94%, Specificity 97%

🧪 Stop PPIs/PCABs 2 wks, antibiotics/bismuth 4 wks before testing.

Choice depends on cost, logistics & patient comfort.

#GastroAGI #HPylori #GastricCancer

🍃Antibiotic Stewardship in H. pylori

Smart use of antibiotics boosts eradication & curbs resistance.

🔹 Apply the 4 Ds: Diagnosis, Drug, Dose, Duration
🔹 Use local resistance data & molecular testing
🔹 Prefer 14-day regimens & confirm cure
🔹 Avoid broad-spectrum misuse

#GastroAGI #HPylori #AntibioticStewardship

✅ H. pylori Testing & Treatment
To check for #HelicobacterPylori, request:
🔬 Urea Breath Test
💩 Stool Antigen Test
⚠️ Blood tests don’t detect active infection or treatment success.

💊 Treatment: Pylera (3-in-1 antibiotics) + acid reducer (e.g., Omeprazole)

Bismuth 140 mg

Metronidazole 125 mg

Tetracycline 125 mg

💰 Approx. price: 120 capsules ≈ 530–545 SAR
⚠️ Prescription required.

#HPylori #StomachHealth #MedicalTips #Gastroenterology #HealthAwareness

جرثومة المعدة (Helicobacter pylori) هي نوع من البكتيريا تُصيب بطانة المعدة، وتُعد من أكثر الأسباب شيوعًا لقرحة المعدة والالتهاب المزمن.

في هذا المقال، سنوضح كل ما تحتاج معرفته: كيف تنتقل؟ ما أعراضها؟ كيف يتم التشخيص؟ وما هو أفضل علاج فعّال لها حسب أحدث التوصيات.

للمزيد من التفاصيل أفرأ المقال بالكامل من خلال هذا اللينك
https://www.thepharmacy.me/hpylori
#جرثومة_المعدة #ألم_المعدة #الارتجاع #أعراض_جرثومة_المعدة #علاج_جرثومة_المعدة #hpylori #health #healthcare

Caltech doctoral student Vida Robertson highlighted a paper in Acta Cryst F, from SBGrid member Craig Smith at Washington University School of Medicine in St. Louis & colleagues.

Read more here: https://buff.ly/oJM3ZtD

#SBGrid #HPylori #Crystallography

🔬 research proposal: presence of H pylori bacteria in people with Primary Ovarian Insufficiency

I learned about #HPylori through an hour or so of internet research so I am qualified to say you should study this 🙃

#Science #Research