Immune escape of Hepatitis B virus (HBV): based on >500 HBV genomes and clinical data we could discover many mutations by which the virus can escape immune recognition. We also show how the adaptation of HBV to the immune system changes over the course of the infection. The key tool in this collaboration of virologists and bioinformaticians was our #Bayesian HAMdetector method.
https://doi.org/10.1016/j.jhep.2024.10.047